Identification of Small Molecules Able to Interfere with Biological Targets Involved in Cancer Pathology

Dear Colleagues,

The increasing understanding and knowledge of the detailed mechanism underlying carcinogenesis provide new strategies and opportunities to identify small molecules able to modulate specific altered cell signalling processes which are, therefore, responsible for the disruption of the normal mechanisms of the regulation of cellular homeostasis.

Many projects, following different strategies, have been focused on the identification of small molecules capable of interacting with innovative biomolecular targets, considered particularly strategic in the context of tumour processes.

The main aim of this Special Issue is to collect and illustrate the recent developments in the field of the identification of target-directed new molecular entities endowed with interesting biological behaviour and considered promising drug candidates.

We invite all researchers working in this field to contribute original articles presenting the results of their research endeavours. Reviews covering the main aspects of this topic are also welcome.

Dr. Ines Bruno
Guest Editor

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• medicinal chemistry
• cancer
• small molecules