Advances in the Synthesis of Xanthene Fluorophores and their Properties
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Colorants".
Deadline for manuscript submissions: closed (31 March 2021) | Viewed by 402
Special Issue Editors
Interests: synthesis of fluorescent chelating ligands and their coordination complexes; xanthene derivatives; porphyrinic macrocycles and analogues; metallo-organic fluorescent materials; NMR spectroscopy
Interests: bioinorganic chemistry; metal ions in biology; iron chelators; EPR spectroscopy; membranes
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Xanthene dyes, including rhodamines, fluoresceins and hybrid rhodol scaffolds, have played a central role in many areas of biochemistry and biology. Offering different degrees of functionalization, xanthene dyes exhibit valuable spectral properties that can be rationally tuned according to the nature and arrangement of substituent groups around the xanthene, constituting a remarkable fodder for the construction of molecules with unique and useful attributes. Through conjugation with biomolecules, xanthenes can be used to create images of tissues or cells. Other modifications, such as the introduction of specific receptors, can be exploited to prepare selective chemosensors for analytes such as cations, anions, pH variations, among others. Additionally, xanthene dyes have been successfully used to construct a number of synthetic dye libraries for discovery of bioactive molecules via phenotypic screening.
This Special Issue intends to give an overview on recent advances in the synthesis and chemical modifications of xanthene skeleton, and modern applications of these molecules in the context of detection, imaging and diagnosis research in life systems.
Dr. Ana Margarida Gomes da Silva
Prof. Dr. Maria Rangel
Guest Editors
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Keywords
- Xanthene dyes
- Synthetic approaches
- Photophysical properties
- Detection
- Imaging
- Diagnosis
