Bioactive Lipids and Cannabinoids, Key Players in Neuropsychiatric Disorders and Beyond
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Bioactive Lipids".
Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 2216
Special Issue Editors
2. Neuroscience Division, School of Biosciences, Cardiff University, Cardiff, UK
Interests: serotonin; GABA; dopamine; epilepsy; addiction; mood disorders; electrophysiology; habenula; basal ganglia; serotonin2 receptors
Special Issues, Collections and Topics in MDPI journals
2. European Center for Brain Research, Santa Lucia Foundation IRCCS, Rome, Italy
Interests: arachidonate cascade; bioactive lipids; biomarkers; cell membranes; endocannabinoids; resolvins; signal transduction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Our body possesses different endogenous signaling systems based on bioactive lipids of which the most investigated class is composed of endocannabinoids (eCBs), known as the endocannabinoid system (ECS). Current knowledge about the pathophysiological role of the main classes of endogenous bioactive lipids, namely glycerophospholipids/sphingolipids, classical eicosanoids and pro-resolving lipid mediators (SPMs), is still limited and further research on this subject is needed. Nevertheless, it is now clear that dysregulated lipid homeostasis contributes greatly to the pathogenesis and even progression of different neurodegenerative diseases.
The elements of ECS have been studied for a long time because they are targeted by ∆-tetrahydrocannabinol (THC) and other plant-derived cannabinoids (phytocannabinoids) and compelling evidence shows that they play a critical role in various developmental processes and brain disorders. While cannabis has an extremely bright future for therapeutic applications, it is not a miracle drug. Phytocannabinoids have been used in medicine for centuries, and over the past decade, the focus has been on their broad therapeutic potential, particularly in seizure management.
The objective of this Special Issue collection is to bring together relevant international researchers from the lipidomics and cannabinoid field to put together an international collection of well-informed opinions, perspectives, and original research articles that evaluate bioactive lipids and cannabinoid compounds in health and disease state.
We invite you to submit contributions in the form of reviews or original research articles that provide new insights into this intriguing research area.
You may choose our Joint Special Issue in IJMS.
Prof. Dr. Giuseppe Di Giovanni
Prof. Dr. Mauro Maccarrone
Guest Editors
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Keywords
- lipidomics
- bioactive lipids
- glycerophospholipids/sphingolipids
- classical eicosanoids
- pro-resolving lipid mediators
- cannabinoids
- glycerophospholipids
- sphingolipids
- classical eicosanoids
- specialized pro-resolving mediators
- phytocannabinoids
- canabidivarin
- cannabidiol
- dosing
- tetrahydrocannabinol
- tetrahydrocannabivarin
- chemical structures
- endocannabinoid system
- CNS diseases
- gut microbiota
- microbiome-gut-brain axis
- CB2 receptor agonists
- synthetic cannabinoids
- neuroprotective
- neuroprotection
- neurodegeneration
- neuroinflammation
- Parkinson's disease
- Huntington's disease
- Tourette's syndrome
- adolescent
- neurodevelopment
- dopamine
- pre-frontal Cortex
- schizophrenia
- addiction
- anxiety
- biomarkers
- autism spectrum disorder
- synthetic cannabinoid use disorder
- cannabinoid use disorder
- global DNA methylation
- NR3C1-specific DNA methylation
- single nucleotide polymorphism
- oxidative and nitrosative stress
- inflammation
- psychiatry
- immunology
- hematology
- human metabolism
- epilepsy
- fertility
- low birthweight
- marijuana
- maternal cannabis use
- menopause
- preterm birth
- reproductive health
- small for gestational age
- substance use
- fear
- anxiety
- networks
- psychopharmacology
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