Bioactive Compounds Derived from Plants and Their Medicinal Potential

Dear Colleagues,

Medicinal plants offer a rich source of pharmaceutical compounds with demonstrated potential to improve and address human and animal diseases, offering important avenues for drug discovery. These bioactive compounds have diverse properties, such as antimicrobial, larvicidal, antioxidant, anticancer, and immunomodulatory activities. Advancements in experimental methodologies, ranging from experimental models and culture systems to microfluidic platforms, have facilitated the study of the bioactivity and pharmacology of these compounds with greater precision and efficiency.

As there have been advances in different technologies, such as data science and machine learning, that have begun to transform evidence-based medicine, particularly at the diagnostics level, we gain a ‘glimpse’ of what next-generation medicine and pharmacy can offer. Despite these advances, in both basic science and technology, clinical translations remain scarce or lagging.

This Special Issue aims to comprehensively gather reports on the bioactivity of several medicinal plants through rigorous experimentation (e.g., in vitro, ex vivo, and in vivo) and advance the development of evidence-based pharmaceutical interventions. The reports can explore various aspects of natural product pharmacology, including the identification of novel compounds, mechanistic studies, synergistic effects, formulation development, and clinical trials. In this collection, we would like to promote some positive paradigm shifts towards more natural and patient-centric therapeutics. Original research and review articles are welcome.

Dr. Maria de Lourdes Pereira
Dr. Veeranoot Nissapatorn
Prof. Dr. Ana Paula Girol
Dr. Sónia M. R. Oliveira
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• phytopharmaceutical drugs
• activity screening (antimicrobial, antioxidant, anticancer, and immunomodulatory activity)
• experimental models (in vitro, ex vivo, in vivo, etc.)
• microfluidic systems