Advances in Pharmacotherapy of Neuropathic Pain

Dear Colleagues,

Advances in the pharmacotherapy for neuropathic pain, which stems from nervous system dysfunction, reflect a growing understanding and targeted approach to address this complex condition. Neuropathic pain arises from the damage or malfunction of the nervous system, manifesting as shooting, burning and tingling sensations, and pain. This type of pain often proves challenging to manage, necessitating specialized treatment strategies. Researchers have investigated drugs such as analgesics, anticonvulsants and antidepressants to alleviate neuropathic pain. In this evolving field, emerging therapies such as cannabinoids and opioids are explored, alongside innovative delivery methods such as topical analgesics. Clinical trials, guided by patient-reported outcomes, contribute to the development of precision medicine tailored to individual needs.

This Special Issue invites both reviews and original articles shedding light on the strategies for pain management. The topics of interest include: drug repositioning;  neurotransmitter modulation; precision medicine approaches; cannabinoids and opioids for neuropathic pain; topical analgesics and innovative delivery methods; neuroplasticity and pain management; patient-reported outcomes in clinical trials; and any future directions and emerging therapies that speculate on the future landscape of neuropathic pain treatment, considering ongoing research and potential breakthroughs.

Prof. Dr. Marucia Chacur
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• analgesic
• inflammation
• neurotransmitters
• neuroplasticity
• targeted therapies
• neurogenic pain
• opioids
• cannabinoids