Advances in Natural Products and Their Derivatives for Metabolic and Chronic Inflammatory Disease Therapy, 2nd Edition

Dear Colleagues,

The 21st century has seen a sharp increase in the incidence of metabolic and chronic diseases, including diabetes, obesity, dyslipidemia, cancer, and chronic inflammatory-related diseases (e.g., rheumatic diseases). Currently, there are several pharmacological approaches to treat these diseases. However, the available therapeutical options are not totally effective, frequently being associated with several adverse effects.

The pharmacological or biological activities of natural products have been intensively explored over the years, resulting in hundreds of molecules presently being used in clinics. Due to their structural diversity, natural products remain a major source and challenge for the identification of novel lead molecules with the potential to treat diseases, namely, metabolic and chronic diseases.

We are pleased to invite you to participate in this Special Issue on “Advances in Natural Products and Their Derivatives for Metabolic and Chronic Inflammatory Disease Therapy” by submitting a contribution in the form of an original research paper, short communication, and/or global or specialized critical review, according to your field of expertise.

This Special Issue aims to explore and describe biological activities, including antioxidant and anti-inflammatory properties, as well as antidiabetic, antiobesogenic, antirheumatic, and anticancer activities of natural products/substances and their derivatives, disclosing their role as possible therapeutic agents for metabolic and chronic inflammatory diseases.

Research in this area has significantly expanded to include the chemical identification of these compounds using advanced analytical techniques, determining their mechanism of action, allowing food fortification and supplement development, and enhancing their bioavailability and bioactivity using, for instance, nanotechnology.

Therefore, the main, but not exclusive, topics to be dealt with in the Special Issue “Advances in Natural Products and Their Derivatives for Metabolic and Chronic Inflammatory Disease Therapy” include the potential treatment of the following diseases, addressing whenever possible, the development of novel methodologies and the establishment of structure–activity relationships:

• Diabetes;
• Obesity;
• Metabolic diseases;
• Inflammation and oxidative-stress related diseases.

We look forward to receiving your contributions.

Dr. Eduarda Fernandes
Dr. Marisa Freitas
Dr. Ana Teresa Rufino
Guest Editors

You may choose our Joint Special Issue in Pharmaceutics.

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• natural products
• metabolic diseases
• chronic inflammation
• drug discovery
• biological activity
• diabetes
• obesity
• rheumatic diseases