Epigenetic Drug Discovery

A special issue of Pharmaceuticals (ISSN 1424-8247).

Deadline for manuscript submissions: closed (15 May 2014) | Viewed by 219

Special Issue Editor


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Guest Editor
Structural Genomics Consortium, University of Oxford, Oxford OX3 7DQ, UK
Interests: target validation; drug discovery; translational science; structural biology; chemical probes and epigenetics

Special Issue Information

Dear Colleagues,

There is currently significant interest in the discovery and development of epigenetic drugs for many chronic diseases, including cancer, inflammatory, metabolic and neuro-psychiatric conditions. It is hypothesised that these may modify the transcription of many causative genes implicated in the development and maintenance of such diseases, and hence inhibitors of these proteins may deliver novel disease modifying therapeutics. There are questions, however, around the tolerability or therapeutic index of such agents. In this issue we will discuss the latest developments in both academia and industry.

Prof. Dr. Chas Bountra
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


Keywords

  • epigenetics
  • drug discovery
  • HDACs
  • bromodomain inhibitors
  • HMT inhibitors

Related Special Issue

Published Papers

There is no accepted submissions to this special issue at this moment.
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