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Pharmaceutics
Special Issues
Polymeric Materials in Drug Delivery Systems
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Polymeric Materials in Drug Delivery Systems

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".

Deadline for manuscript submissions: closed (25 April 2023) | Viewed by 4541

Special Issue Editors

Dr. Patrícia Alves

E-Mail Website
Guest Editor
Department of Chemical Engineering, Chemical Process Engineering and Forest Products Research Centre (CIEPQPF), University of Coimbra, 3030-790 Coimbra, Portugal
Interests: surface modification; smart materials; drug delivery; biomaterials; polymers; liposomes
Special Issues, Collections and Topics in MDPI journals
Dr. Paula Ferreira

E-Mail Website
Guest Editor
Polytechnic Institute of Coimbra, Superior Institute of Engineering of Coimbra, 3030-199 Coimbra, Portugal
Interests: polymers; biomaterials; drug delivery; tissue engineering
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Formulations that control the rate and period of drug delivery (i.e., time-release medications) and target specific areas of the body for treatment have become increasingly common and complex. Over the past few decades, drug delivery has remarkably advanced and is clearly moving from the micro- to the nanoscale, and polymers play an important role here. Drug delivery systems aim to carry therapeutic substances to targeted parts of the body, without reaching nontarget cells, organs, or tissues and at the same time control the therapy administration by means of either a physiological or chemical trigger. Over the years, polymeric micro/nanospheres, polymer micelles, biodegradable polymers, dendrimers, nanoparticles, liposomes, and hydrogel-based materials have all been shown to be effective in enhancing drug-targeting specificity, lowering systemic drug toxicity, improving treatment absorption rates, and providing protection for pharmaceuticals against biochemical degradation.

Within this topic, we are pleased to invite you to contribute with a full article, short communication, or review article to this Special Issue entitled “Polymeric Materials in Drug Delivery Systems”.

Dr. Patrícia Alves
Dr. Paula Ferreira
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • drug delivery
  • therapeutic agents
  • responsive polymers
  • hydrogels
  • tissue engineering
  • polymeric materials
  • biomaterials
  • nanoparticles

Published Papers (2 papers)

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Review

36 pages, 6527 KiB  
Review
Cryogels: Advancing Biomaterials for Transformative Biomedical Applications
by Hossein Omidian, Sumana Dey Chowdhury and Niloofar Babanejad
Pharmaceutics 2023, 15(7), 1836; https://doi.org/10.3390/pharmaceutics15071836 - 27 Jun 2023
Cited by 8 | Viewed by 2311
Abstract
Cryogels, composed of synthetic and natural materials, have emerged as versatile biomaterials with applications in tissue engineering, controlled drug delivery, regenerative medicine, and therapeutics. However, optimizing cryogel properties, such as mechanical strength and release profiles, remains challenging. To advance the field, researchers are [...] Read more.
Cryogels, composed of synthetic and natural materials, have emerged as versatile biomaterials with applications in tissue engineering, controlled drug delivery, regenerative medicine, and therapeutics. However, optimizing cryogel properties, such as mechanical strength and release profiles, remains challenging. To advance the field, researchers are exploring advanced manufacturing techniques, biomimetic design, and addressing long-term stability. Combination therapies and drug delivery systems using cryogels show promise. In vivo evaluation and clinical trials are crucial for safety and efficacy. Overcoming practical challenges, including scalability, structural integrity, mass transfer constraints, biocompatibility, seamless integration, and cost-effectiveness, is essential. By addressing these challenges, cryogels can transform biomedical applications with innovative biomaterials. Full article
(This article belongs to the Special Issue Polymeric Materials in Drug Delivery Systems)
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11 pages, 954 KiB  
Review
Topical Drug Delivery in the Treatment of Skin Wounds and Ocular Trauma Using the Platform Wound Device
by Elof Eriksson, Gina L Griffith and Kristo Nuutila
Pharmaceutics 2023, 15(4), 1060; https://doi.org/10.3390/pharmaceutics15041060 - 25 Mar 2023
Cited by 1 | Viewed by 1960
Abstract
Topical treatment of injuries such as skin wounds and ocular trauma is the favored route of administration. Local drug delivery systems can be applied directly to the injured area, and their properties for releasing therapeutics can be tailored. Topical treatment also reduces the [...] Read more.
Topical treatment of injuries such as skin wounds and ocular trauma is the favored route of administration. Local drug delivery systems can be applied directly to the injured area, and their properties for releasing therapeutics can be tailored. Topical treatment also reduces the risk of adverse systemic effects while providing very high therapeutic concentrations at the target site. This review article highlights the Platform Wound Device (PWD) (Applied Tissue Technologies LLC, Hingham, MA, USA) for topical drug delivery in the treatment of skin wounds and eye injuries. The PWD is a unique, single-component, impermeable, polyurethane dressing that can be applied immediately after injury to provide a protective dressing and a tool for precise topical delivery of drugs such as analgesics and antibiotics. The use of the PWD as a topical drug delivery platform has been extensively validated in the treatment of skin and eye injuries. The purpose of this article is to summarize the findings from these preclinical and clinical studies. Full article
(This article belongs to the Special Issue Polymeric Materials in Drug Delivery Systems)
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