Long-Acting Drug Delivery Strategies for Precision Nanomedicine
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 1411
Special Issue Editor
2. Josep Carreras Leukaemia Research Institute, 08025 Barcelona, Spain
3. CIBER de Bioingeniería, Biomateriales y Nanomedicina, Instituto de Salud Carlos III, Majadahonda, Spain
4. Departament de Genètica i de Microbiologia, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain
Interests: nanomedicine; cancer therapy; protein materials; targeting; drug delivery systems; self-assembling
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In the development of precision nanomedicines, many efforts are being made in order to improve the pharmacokinetics of administered drugs, as this is an effective way to enhance their therapeutic outcome. In this sense, current therapies are still mainly based on the intravenous administration of small molecules, which show short biological half-lives and, in consequence, require multiple doses. This administration pattern, far from being effective, generates large fluctuations in blood drug concentration and significantly increases the risk of potential side effects, strongly limiting their use in clinic. Therefore, there is an urgent need to develop innovative, long-acting drug delivery systems that allow the sustained-release of the administered drug over a long period of time, from several days to weeks. This approach not only significantly enhances the pharmacokinetics of the drug by maintaining its constant level in the blood during the treatment, but also improves patients quality of life and increases adherence to the therapy.
This Special Issue entitled “Long-Acting Drug Delivery Strategies for Precision Nanomedicine” expects to collect current research progresses in the development of therapeutic drug delivery systems, that allow the sustained release of different types of drugs into de blood stream for improved pharmacokinetics and therapeutic efficiency. Therefore, this Special Issue invites all researchers working on this field to contribute with their original research articles and reviews.
Dr. Ugutz Unzueta
Guest Editor
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Keywords
- nanomedicine
- drug delivery system
- sustained release
- pharmacokinetics
