Functionalized Nanomaterials for Cancer Therapy

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".

Deadline for manuscript submissions: closed (20 April 2023) | Viewed by 1706

Special Issue Editor


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Guest Editor
Department of Medicinal Chemistry, College of Pharmaceutical Science, Capital Medical University, Beijing 100069, China
Interests: metal-based drugs; self-assembly; PAD4 inhibitors; nanomedicine

Special Issue Information

Dear Colleagues,

Cancer is still an incurable disease, and traditional treatment methods, such as chemotherapy and radiotherapy, have certain limitations. The emergence of functionalized nanomaterials provides a new possibility for cancer treatment. Tumor targeting based on the enhanced permeability and retention (EPR) effect has been an important direction to reduce drug toxicity. Multifunctional nanomaterials also make combination therapy possible, such as photodynamic therapy (PDT), photothermal therapy (PTT), immunotherapy, etc. Nanomaterials are also used for visualization applications in the process of cancer treatment, such as magnetic resonance image (MRI); positron emission tomography/computed tomography (PET/CT), and fluorescence imaging (FI). Therefore, the application of functionalized nanomaterials in cancer treatment is worth summarizing, and is also expected to play a new role in the development of cancer.

Prof. Dr. Yuji Wang
Guest Editor

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Keywords

  • nanomaterials
  • self-assembly
  • nano drug delivery system (NDDS)
  • antitumor
  • antimetastasis
  • nanoparticle contrast agent

Published Papers (1 paper)

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Review

36 pages, 11133 KiB  
Review
Applications of Degradable Hydrogels in Novel Approaches to Disease Treatment and New Modes of Drug Delivery
by Bo Hu, Jinyuan Gao, Yu Lu and Yuji Wang
Pharmaceutics 2023, 15(10), 2370; https://doi.org/10.3390/pharmaceutics15102370 - 22 Sep 2023
Cited by 2 | Viewed by 1345
Abstract
Hydrogels are particularly suitable materials for loading drug delivery agents; their high water content provides a biocompatible environment for most biomolecules, and their cross-linked nature protects the loaded agents from damage. During delivery, the delivered substance usually needs to be released gradually over [...] Read more.
Hydrogels are particularly suitable materials for loading drug delivery agents; their high water content provides a biocompatible environment for most biomolecules, and their cross-linked nature protects the loaded agents from damage. During delivery, the delivered substance usually needs to be released gradually over time, which can be achieved by degradable cross-linked chains. In recent years, biodegradable hydrogels have become a promising technology in new methods of disease treatment and drug delivery methods due to their many advantageous properties. This review briefly discusses the degradation mechanisms of different types of biodegradable hydrogel systems and introduces the specific applications of degradable hydrogels in several new methods of disease treatment and drug delivery methods. Full article
(This article belongs to the Special Issue Functionalized Nanomaterials for Cancer Therapy)
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