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Technology Trends in Fluorescence Detection Based on Biosensor

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: 5 December 2024 | Viewed by 1139

Special Issue Editors


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Guest Editor
School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan
Interests: lipid membrane; bio-analysis; biosensor
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Health and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba 305-8566, Ibaraki, Japan
Interests: molecular sensors; molecular assemblies; molecular devices

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Guest Editor
School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan
Interests: microfluidics; lab-on-a-chip; sensor material

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Guest Editor
School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan
Interests: sensor development targeting tay molecular weight compounds such as drugs

Special Issue Information

Dear Colleagues,

Fluorescence-based sensors have been a growing research field for many years. Among fluorescent sensors, biosensors have progressed remarkably, and many researchers have developed superior sensors that can measure not only biological macromolecules such as proteins and nucleic acids, but also small molecules such as amino acids, sugars, and pharmaceuticals. Therefore, these are becoming an indispensable measurement technology in the fields of pharmaceuticals, agriculture, and the environment. If fluorescent probes are also considered a category of sensors, fluorescent imaging techniques using these probes are very useful for solving unknown biological processes in tissues or cells. On the other hand, sensors for on-site analysis must be usable by anyone, anywhere, at any time, and therefore measurement operation must be not only very simple but also quick. Increasing the sensitivity of these sensors is an important mission, and an approach to solving this problem has been reported using the phenomenon of fluorescence intensity enhancement through the use of inorganic metal nanomaterials. In this Special Issue, we welcome submissions of papers that introduce new principles of sensors and applications of sensors to discuss new possibilities of fluorescence-based sensors, which are making remarkable progress as described above.

Dr. Atsushi Shoji
Dr. Tsukuru Minamiki
Dr. Kazuhiro Morioka
Dr. Yukiko Moriiwa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • on-site analysis
  • cell analysis
  • imaging
  • fluorescent protein
  • fluorescent quantum dot
  • fluorescent polymer
  • fluorescence particle
  • microlfluidics
  • lab-on-a-chip

Published Papers (1 paper)

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Research

9 pages, 2941 KiB  
Communication
Near-Infrared Fluorescence Imaging Sensor with Laser Diffuser for Visualizing Photoimmunotherapy Effects under Endoscopy
by Toshihiro Takamatsu, Hideki Tanaka and Tomonori Yano
Sensors 2024, 24(5), 1487; https://doi.org/10.3390/s24051487 - 25 Feb 2024
Viewed by 777
Abstract
The drug efficacy evaluation of tumor-selective photosensitive substances was expected to be enabled by imaging the fluorescence intensity in the tumor area. However, fluorescence observation is difficult during treatments that are performed during gastrointestinal endoscopy because of the challenges associated with including the [...] Read more.
The drug efficacy evaluation of tumor-selective photosensitive substances was expected to be enabled by imaging the fluorescence intensity in the tumor area. However, fluorescence observation is difficult during treatments that are performed during gastrointestinal endoscopy because of the challenges associated with including the fluorescence filter in the camera part. To address this issue, this study developed a device that integrates a narrow camera and a laser diffuser to enable fluorescence imaging through a forceps port. This device was employed to demonstrate that a laser diffuser with an NIR fluorescence imaging sensor could be delivered through a 3.2 mm diameter port. In addition, fluorescence images of Cetuximab-IR700 were successfully observed in two mice, and the fluorescence intensity confirmed that the fluorescence decayed within 330 s. This device is expected to have practical application as a tool to identify the optimal irradiation dose for tumor-selective photosensitive substances under endoscopy. Full article
(This article belongs to the Special Issue Technology Trends in Fluorescence Detection Based on Biosensor)
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

 
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