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Microfluidic Devices for Bioactive Compound Monitoring

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: closed (31 January 2021) | Viewed by 3705

Special Issue Editors


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Guest Editor
NASA Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Dr., Pasadena, CA 91109, USA
Interests: electroanalytical chemistry; electrophoretic separations; miniaturization of analytical systems; microchip electrophoresis; microfluidic-paper-based analytical devices (µPADs); biosignatures and astrobiology

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Guest Editor
Department of Chemistry, Clemson University, Clemson, SC 29634, USA
Interests: nanomaterials; protein interactions; biosensors; separations
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In the last few decades, bioactive compounds have attracted the attention of researchers worldwide due to their potential to benefit human health. Their effect on physiological, behavioral, and immunological responses has been extensively evaluated. This ever-increasing interest in monitoring bioactive compounds has created demand for sensitive and reliable analytical techniques that combine a short analysis time, portability, versatility, and a low cost.

For this Special Issue, entitled “Microfluidic Devices for Bioactive Compound Monitoring”, we welcome the submission of original research and review articles that focus on the development and/or application of microfluidic devices for the analysis of bioactive compounds, including carotenoids, flavonoids, polyphenols, phytosterols, phytoestrogens, glucosinolates, dithiolthiones, terpenoids, alkaloids, glycosides, and vitamins. Articles with a high level of scientific rigor will be considered for peer review.

Dr. Mauro Sergio Ferreira Santos
Prof. Dr. Carlos D. Garcia
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • microchip
  • microfluidic devices
  • lab-on-a-chip
  • bioactive molecules
  • antioxidants
  • anti-carcinogenic
  • anti-inflammatory
  • anti-microbial
  • anti-allergic

Published Papers (1 paper)

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9 pages, 1483 KiB  
Letter
A Multi-Pump Magnetohydrodynamics Lab-On-A-Chip Device for Automated Flow Control and Analyte Delivery
by Rafael M. Cardoso, Robson O. dos Santos, Rodrigo A. A. Munoz, Carlos D. Garcia and Lucas Blanes
Sensors 2020, 20(17), 4909; https://doi.org/10.3390/s20174909 - 31 Aug 2020
Cited by 8 | Viewed by 3381
Abstract
This article shows the development of a computer-controlled lab-on-a-chip device with three magnetohydrodynamic (MHD) pumps and a pneumatic valve. The chip was made of a stack of layers of polymethylmethacrylate (PMMA), cut using a laser engraver and thermally bonded. The MHD pumps were [...] Read more.
This article shows the development of a computer-controlled lab-on-a-chip device with three magnetohydrodynamic (MHD) pumps and a pneumatic valve. The chip was made of a stack of layers of polymethylmethacrylate (PMMA), cut using a laser engraver and thermally bonded. The MHD pumps were built using permanent magnets (neodymium) and platinum electrodes, all of them controlled by an Arduino board and a set of relays. The implemented pumps were able to drive solutions in the open channels with a flow rate that increased proportionally with the channel width and applied voltage. To address the characteristic low pressures generated by this kind of pump, all channels were interconnected. Because the electrodes were immersed in the electrolyte, causing electrolysis and pH variations, the composition and ionic strength of the electrolyte solution were controlled. Additionally, side structures for releasing bubbles were integrated. With this multi-pump and valve solution, the device was used to demonstrate the possibility of performing an injection sequence in a system that resembles a traditional flow injection analysis system. Ultimately, the results demonstrate the possibility of performing injection sequences using an array of MHD pumps that can perform fluid handling in the 0–5 µL s−1 range. Full article
(This article belongs to the Special Issue Microfluidic Devices for Bioactive Compound Monitoring)
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