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Modern Sensor Technology in Ophthalmology and Optometry for Diagnostics and Surgery

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biomedical Sensors".

Deadline for manuscript submissions: 31 July 2024 | Viewed by 3023

Special Issue Editors

Prof. Dr. Bojan Pajic

E-Mail Website1 Website2
Guest Editor
1. Eye Clinic Orasis, Swiss Eye Research Foundation, 5734 Reinach AG, Switzerland
2. Division of Ophthalmology, Department of Clinical Neurosciences, Geneva University Hospitals, Geneva, Switzerland
Interests: femtosecond laser technology; excimer laser and ablative solid state laser technology; diagnostic diode laser; corneal biomechanics; corneal surgery procedure; mathematical models for corneal biomechanics; corneal presbyopia procedure; autologous corneal inlay; cataract surgery techniques; high frequency deep sclerotomy (HFDS) glaucoma procedure; clinical trial in cataract, cornea and glaucoma surgery
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Željka Cvejić

E-Mail Website
Guest Editor
Department of Physics, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovića 4, 21000 Novi Sad, Serbia
Interests: structure and microstructure; design and optimization of electrical, magnetic and optical properties of nanomaterials; biomedical structural analysis; X-ray diffraction; Raman spectroscopy and imaging; vibrational spectroscopy; scattering; structure modelling, optometry and vision science
Special Issues, Collections and Topics in MDPI journals
Dr. Dragan Indjin

E-Mail Website
Guest Editor
Optoelectronics and Nanoscale Electronics, Pollard Institute, School of Electronic and Electrical Engineering, University of Leeds, Woodhouse Lane, Leeds LS2 9JT, UK
Interests: optical absorption; semiconductor lasers; mid-infrared and terahertz lasers and detectors; quantum-cascade lasers; infrared and terahertz sensing and imaging, medical sensing and imaging
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The global improvement of health care is based on innovative scientific research with the development of new technologies. The Special Issue “Modern Sensor Technology in Ophthalmology and Optometry for Diagnostics and Surgery” aims to publish comprehensive and relevant research results from all scientific and technical disciplines, including ophthalmology, vision sciences, optometry and physics of the eye. An essential factor of importance in ophthalmology and optometry is the interdisciplinary development. This includes both basic research, which deals with physical, chemical and biological phenomena in the eye, and clinical research, which focuses on the development and optimisation of technical technologies and sensors in ophthalmology. The interaction and collaboration of physicists, engineers, ophthalmologists and optometrists is nowadays indispensable for the development of relevant cutting-edge technologies. The results potentially lead to the further development of state-of-the-art medicine. The main task is to enable patients to be diagnosed as quickly and accurately as possible and to help them in a minimally invasive manner, both conservatively and surgically. In the surgical disciplines in particular, the aim is to keep the patient’s rehabilitation time as short as possible while achieving maximum results. We would like to encourage research groups with relevant expertise to publish papers in this Special Issue that pursue precisely these goals and demonstrate and illustrate the importance of interdisciplinary approaches in the sensor technology for diagnostics and surgery in ophthalmology.

Prof. Dr. Bojan Pajic
Prof. Dr. Željka Cvejić
Dr. Dragan Indjin
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • sensors in ophthalmology
  • sensors in optometry
  • medical sensors
  • mathematical modelling
  • biomechanical modelling
  • optical aberrations
  • vision care
  • surgery in ophthalmology
  • lasers in ophthalmology for diagnostics and surgery

Published Papers (2 papers)

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Research

10 pages, 2359 KiB  
Communication
Two-Photon Excited Fluorescence Lifetime Imaging of Tetracycline-Labeled Retinal Calcification
by Kavita R. Hegde, Krishanu Ray, Henryk Szmacinski, Sharon Sorto, Adam C. Puche, Imre Lengyel and Richard B. Thompson
Sensors 2023, 23(14), 6626; https://doi.org/10.3390/s23146626 - 24 Jul 2023
Cited by 1 | Viewed by 886
Abstract
Deposition of calcium-containing minerals such as hydroxyapatite and whitlockite in the subretinal pigment epithelial (sub-RPE) space of the retina is linked to the development of and progression to the end-stage of age-related macular degeneration (AMD). AMD is the most common eye disease causing [...] Read more.
Deposition of calcium-containing minerals such as hydroxyapatite and whitlockite in the subretinal pigment epithelial (sub-RPE) space of the retina is linked to the development of and progression to the end-stage of age-related macular degeneration (AMD). AMD is the most common eye disease causing blindness amongst the elderly in developed countries; early diagnosis is desirable, particularly to begin treatment where available. Calcification in the sub-RPE space is also directly linked to other diseases such as Pseudoxanthoma elasticum (PXE). We found that these mineral deposits could be imaged by fluorescence using tetracycline antibiotics as specific stains. Binding of tetracyclines to the minerals was accompanied by increases in fluorescence intensity and fluorescence lifetime. The lifetimes for tetracyclines differed substantially from the known background lifetime of the existing natural retinal fluorophores, suggesting that calcification could be visualized by lifetime imaging. However, the excitation wavelengths used to excite these lifetime changes were generally shorter than those approved for retinal imaging. Here, we show that tetracycline-stained drusen in post mortem human retinas may be imaged by fluorescence lifetime contrast using multiphoton (infrared) excitation. For this pilot study, ten eyes from six anonymous deceased donors (3 female, 3 male, mean age 83.7 years, range 79–97 years) were obtained with informed consent from the Maryland State Anatomy Board with ethical oversight and approval by the Institutional Review Board. Full article
(This article belongs to the Special Issue Modern Sensor Technology in Ophthalmology and Optometry for Diagnostics and Surgery)
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8 pages, 751 KiB  
Article
Development and Testing of a Compact Autorefractor Based on Double-Pass Imaging
by Linus Emmerich, Arne Ohlendorf, Alexander Leube, Nikolai Suchkov and Siegfried Wahl
Sensors 2023, 23(1), 362; https://doi.org/10.3390/s23010362 - 29 Dec 2022
Cited by 1 | Viewed by 1660
Abstract
Autorefraction is an objective way to determine the refractive error of the eye, without the need for feedback by the patient or a well-educated practitioner. To make refractive measurements more accessible in the background of the growing prevalence of myopia, a compact autorefractor [...] Read more.
Autorefraction is an objective way to determine the refractive error of the eye, without the need for feedback by the patient or a well-educated practitioner. To make refractive measurements more accessible in the background of the growing prevalence of myopia, a compact autorefractor was built, containing only few optical components and relying on double-pass imaging and the physical properties of the point-spread function and digital image processing instead. A method was developed to analyze spherical defocus as well as the defocus and angle of astigmatism. The device was tested using calibrator eye models in a range of ± 15 D spherical defocus and −3 D astigmatic defocus. Reliable results could be achieved across the whole measurement range, with only a small increase in deviation toward high values of refractive errors, showing the feasibility of a PSF-based approach for a compact and low-cost solution for objective measurements of refractive error. Full article
(This article belongs to the Special Issue Modern Sensor Technology in Ophthalmology and Optometry for Diagnostics and Surgery)
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