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New Strategies and Current Challenges for Label-Free Biosensors Improvement

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: closed (30 September 2022) | Viewed by 2544

Special Issue Editors


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Guest Editor
Laboratoire Nanotechnologies Nanosystèmes (LN2 – IRL 3463) - CNRS, Université de Sherbrooke - Institut Interdisciplinaire d’Innovation Technologique (3IT), 3000 Boulevard de l’université, Sherbrooke, QC J1K OA5, Canada
Interests: thermoplasmonics; Raman spectroscopy; nanophotonics; pump–probe spectroscopy; SPR sensors; plasmonics

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Guest Editor
Institut Jean Lamour, UMR 7198-CNRS, Nancy F-54000, France
Interests: acoustic wave devices; mechanobiology; gas sensors

Special Issue Information

Dear Colleagues,

Current events have shown the necessity to perform a fast, efficient, and straightforward detection of low concentrations of organic elements. In this period of the global COVID-19 pandemic, most clinical testing occurs in large, centralized laboratories to concentrate operations in a single location for cost savings and standardized results. With standardization, protocols are optimized for training staff, yielding minimum delays and controllable budget objectives. However, centralized laboratory-based testing is heavily dependent on advanced technologies that increase in costs that are becoming prohibitive for all but the richest countries.

Biosensors are once again highlighted as the technologies able to respond quickly to a need for simple and reliable detection requiring no specific knowledge, low reagent, and massive production to address the important societal challenge of providing quality health care at affordable costs for all by “doing more with less”.

This Special Issue solicits innovative contributions from both industry and academia in biosensing areas covered by a wide range of devices, based on optical, acoustical, chemical, thermal, new materials and electrical parameters but not only. New strategies in micropatterning functionalization or biosensor design are also welcomed.

Dr. Jean-François Bryche
Prof. Frédéric Sarry
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Active transport 
  • Acoustic 
  • Plasmonics 
  • Nanobiosensing 
  • Photonic biosensors 
  • Raman spectroscopy 
  • Plasmonics materials 
  • Innovative biosensors design 
  • Nanoparticle 
  • Micropatterning functionalization

Published Papers (1 paper)

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Review

39 pages, 5917 KiB  
Review
Bio-Tailored Sensing at the Nanoscale: Biochemical Aspects and Applications
by Francesca Fata, Federica Gabriele, Francesco Angelucci, Rodolfo Ippoliti, Luana Di Leandro, Francesco Giansanti and Matteo Ardini
Sensors 2023, 23(2), 949; https://doi.org/10.3390/s23020949 - 13 Jan 2023
Cited by 1 | Viewed by 2086
Abstract
The demonstration of the first enzyme-based electrode to detect glucose, published in 1967 by S. J. Updike and G. P. Hicks, kicked off huge efforts in building sensors where biomolecules are exploited as native or modified to achieve new or improved sensing performances. [...] Read more.
The demonstration of the first enzyme-based electrode to detect glucose, published in 1967 by S. J. Updike and G. P. Hicks, kicked off huge efforts in building sensors where biomolecules are exploited as native or modified to achieve new or improved sensing performances. In this growing area, bionanotechnology has become prominent in demonstrating how nanomaterials can be tailored into responsive nanostructures using biomolecules and integrated into sensors to detect different analytes, e.g., biomarkers, antibiotics, toxins and organic compounds as well as whole cells and microorganisms with very high sensitivity. Accounting for the natural affinity between biomolecules and almost every type of nanomaterials and taking advantage of well-known crosslinking strategies to stabilize the resulting hybrid nanostructures, biosensors with broad applications and with unprecedented low detection limits have been realized. This review depicts a comprehensive collection of the most recent biochemical and biophysical strategies for building hybrid devices based on bioconjugated nanomaterials and their applications in label-free detection for diagnostics, food and environmental analysis. Full article
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