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Carbon Paste Electrodes

A special issue of Sensors (ISSN 1424-8220).

Deadline for manuscript submissions: closed (30 April 2005) | Viewed by 20409

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Guest Editor
Faculty of Science, Department of Analytical Chemistry, UNESCO Laboratory of Environmental Electrochemistry, Charles University, CZ 128 43 Prague Praha, Czech Republic
Interests: voltammetry; amperometry; electrochemistry in flowing systems; novel electrode materials; electrochemical sensors

Special Issue Information

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Published Papers (2 papers)

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Research

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242 KiB  
Article
Brain Tissue Oxygen: In Vivo Monitoring with Carbon Paste Electrodes
by Fiachra B. Bolger and John P. Lowry
Sensors 2005, 5(11), 473-487; https://doi.org/10.3390/s5110473 - 16 Nov 2005
Cited by 36 | Viewed by 9073
Abstract
In this communication we review selected experiments involving the use ofcarbon paste electrodes (CPEs) to monitor and measure brain tissue O2 levels in awakefreely-moving animals. Simultaneous measurements of rCBF were performed using the H2clearance technique. Voltammetric techniques used include both [...] Read more.
In this communication we review selected experiments involving the use ofcarbon paste electrodes (CPEs) to monitor and measure brain tissue O2 levels in awakefreely-moving animals. Simultaneous measurements of rCBF were performed using the H2clearance technique. Voltammetric techniques used include both differential pulse (O2) andconstant potential amperometry (rCBF). Mild hypoxia and hyperoxia produced rapidchanges (decrease and increase respectively) in the in vivo O2 signal. Neuronal activation(tail pinch and stimulated grooming) produced similar increases in both O2 and rCBFindicating that CPE O2 currents provide an index of increases in rCBF when such increasesexceed O2 utilization. Saline injection produced a transient increase in the O2 signal whilechloral hydrate produced slower more long-lasting changes that accompanied the behavioralchanges associated with anaesthesia. Acetazolamide increased O2 levels through an increasein rCBF. Full article
(This article belongs to the Special Issue Carbon Paste Electrodes)
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Review

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207 KiB  
Review
Long-Term Monitoring of Brain Dopamine Metabolism In Vivo with Carbon Paste Electrodes
by Robert D. O’Neill
Sensors 2005, 5(6), 317-342; https://doi.org/10.3390/s5060317 - 14 Nov 2005
Cited by 26 | Viewed by 10599
Abstract
This review focuses on the stability of voltammetric signals recorded overperiods of months with carbon paste electrodes (CPEs) implanted in the brain. The keyinteraction underlying this stability is between the pasting oil and brain lipids that arecapable of inhibiting the fouling caused by [...] Read more.
This review focuses on the stability of voltammetric signals recorded overperiods of months with carbon paste electrodes (CPEs) implanted in the brain. The keyinteraction underlying this stability is between the pasting oil and brain lipids that arecapable of inhibiting the fouling caused by proteins. In brain regions receiving a significantdopaminergic input, a peak due to the methylated metabolites of dopamine, principallyhomovanillic acid (HVA), is clearly resolved using slow sweep voltammetry. Although anumber of factors limit the time resolution for monitoring brain HVA concentrationdynamics, the stability of CPEs allows investigations of long-term effects of drugs, as wellas behavioral studies, not possible using other in-vivo monitoring techniques. Full article
(This article belongs to the Special Issue Carbon Paste Electrodes)
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