Peptide Synthesis, Separation and Purification

Dear Colleagues,

Synthetic peptide manufacturing is substantially more expensive than small molecule manufacturing. Additionally, the larger the API molecule becomes, efficient purification and isolation becomes increasingly more important as well. The demand particularly increases as production quantities from tens to thousands of kilograms per year.

Given this context, this Special Issue of Separations, ‘Peptide Synthesis, Separation and Purification,’ invites scholars to submit their original research and review articles, covering various aspects of peptides purification including the synthetic approaches, separation methodologies, and the influence of hydrophobicity and solubility on the overall separation and purification behavior. Furthermore, we welcome papers addressing novel synthetic strategies that can deliver purer peptides and decrease the purification burden, as well as papers that incorporate computational, modeling, and machine learning approaches as these are powerful tools that can save time, cost, and effort.

Dr. Othman Al Musaimi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Separations is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• hydrophobicity
• retention time prediction
• solubility
• retention behavior
• peptide separation
• purification
• denaturation