DNA Damage Response to Harmful Anthropogenic Substances
A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Exposome Analysis and Risk Assessment".
Deadline for manuscript submissions: closed (15 September 2020) | Viewed by 11705
Special Issue Editor
Interests: human biomonitoring; genetic toxicology; chemical mixtures; risk assessment; occupational health; in vitro
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
DNA is the repository of genetic information and its integrity and stability are crucial to life, thus there exist robust and efficient DNA repair systems. In addition to the intrinsic genetic insults from DNA replication during cell division, DNA oxidative damage from byproducts of metabolism—such as free radicals, and others—environmental agents can also interact with and damage DNA. The problematic issue of unrepaired DNA damage is the possibility of mutation and possibly disease, namely cancer, which is a genetic disease. There is a wide range of anthropogenic sources of harmful substances produces by the metallurgical industry, energy production by combustion, cooking, road traffic, waste treatment, industrial organics, and pesticides, among others, which can be found in the environment and/or in occupational contexts.
This Special Issue on “DNA damage responses to harmful anthropogenic substances” aims to highlight the research into DNA damage as an effect biomarker in the study of the effects, processes, objects, or materials derived from human activities, including all forms of chemical, physical and biological substances.
Authors are invited and welcome to submit original research papers, reviews, and short communications.
Prof. Carina Ladeira
Guest Editor
Manuscript Submission Information
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Keywords
- DNA damage
- biomarker
- environment occupational
- exposure
- anthropogenic
- toxicants
- risk assessment
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