Toxics

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Special Issue Editor

Prof. Dr. Qingming Zhang

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Guest Editor

College of Plant Health and Medicine, Qingdao Agricultural University, Qingdao 266109, China
Interests: pesticide risk assessment; environmental chemistry; pesticide pollution remediation; soil biology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In the last few decades, pesticides have played an irreplaceable role in agricultural practice for controlling pests and increasing crop yield and quality. However, the inefficient and extensive use of pesticides inadvertently results in environmental pollution and produces toxic effects in non-target organisms and on human health. Therefore, thoroughly understanding the environmental behavior and potential ecotoxicity of pesticide exposure are vitally important for pesticides’ environmental safety and scientific application. Moreover, the development of new or systematic pesticide exposure risk assessment methods is also crucial for the clarification/analysis of the risk of pesticides in complex real-world environments.

This Special Issue on “Ecotoxicity Induced by Pesticides Exposure Volume II” aims to gather studies covering various aspects of this topic, and we encourage scientists around the world to contribute original research papers and reviews dealing with the ecotoxicity and risk assessment of pesticide exposure. Articles may include but are not limited to the following topics:

Ecotoxicity to non-target organisms
Ecological risk assessment
Mixture toxicity
Stereoselective toxicity
Aquatic toxicology
Risk assessment method
Toxicity reduction strategy
Multiple omics analysis of toxicity
Toxic mechanism
Toxicological model.

Prof. Dr. Qingming Zhang
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Related Special Issue

Published Papers (1 paper)

Research

15 pages, 1286 KiB

Open AccessArticle

Microarray and Functional Pathway Analyses Revealed Significantly Elevated Gene Expressions Associated with Metabolic Resistance to Oxamyl (Vydate) in Lygus lineolaris

by Yu-Cheng Zhu, Yuzhe Du, Xiaofen Liu, Maribel Portilla, Jian Chen and Yanhua Wang

Toxics 2024, 12(3), 188; https://doi.org/10.3390/toxics12030188 - 28 Feb 2024

Viewed by 932

Abstract

The tarnished plant bug (TPB, Lygus lineolaris) remains a major pest for a variety of crops. Frequent sprays on row crops, especially cotton, prompted resistance development in field populations. To maintain chemical control as an effective tool against the pest, knowledge of global gene regulations is desirable for better understanding and managing the resistance. Novel microarray expressions of 6688 genes showed 685 significantly upregulated and 1382 significantly downregulated genes in oxamyl-selected TPBs (Vyd1515FF[R]) from a cotton field. Among the 685 upregulated genes (participated in 470 pathways), 176 genes code 30 different enzymes, and 7 of the 30 participate in 24 metabolic pathways. Six important detoxification pathways were controlled by 20 genes, coding 11 esterases, two P450s, two oxidases, and three pathway-associated enzymes (synthases, reductase, and dehydrogenase). Functional analyses showed substantially enhanced biological processes and molecular functions, with hydrolase activity as the most upregulated molecular function (controlled by 166 genes). Eleven esterases belong to the acting on ester bond subclass of the 166 hydrolases. Surprisingly, only one GST showed significant upregulation, but it was not involved in any detoxification pathway. Therefore, this research reports a set of 20 genes coding 6 enzyme classes to detoxify a carbamate insecticide oxamyl in Vyd1515FF. Together with three previous reports, we have obtained the best knowledge of resistance mechanisms to all four conventional insecticide classes in the economically important crop pest. This valuable finding will greatly facilitate the development of molecular tools to monitor and manage the resistance and to minimize risk to environment. Full article

(This article belongs to the Special Issue Ecotoxicity Induced by Pesticides Exposure Volume II)

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