Distribution, Metabolism, and Toxicity Exposure of Emerging Toxics

Dear Colleagues,

Emerging organic chemicals are designed and produced for the growing demand of novel industrial and commercial products. Nevertheless, most of them are frequently detected in water, soil, air, sediment and biota. Furthermore, their metabolic products are monitored in human urine, blood, hair or breast milk. In vivo and in vitro studies have unraveled that these toxics exhibit negative effects on human health, including neuro-behavioral deficits, reproductive toxicity, immunotoxicity and endocrine-disturbing effects. The metabolism of organic pollutants by microorganisms, animals, plants and humans is an important function of the environment, possibly altering the fate and ecological risk of these toxics and their metabolites. More specifically, some metabolites of emerging toxins may exhibit higher toxicity and bioaccumulation than their parent toxins, which has been often neglected. Further research on the fate, metabolism and toxicity exposure of emerging toxidcs needs to be accomplished and improved, aiming to elucidate their toxicity mechanism and potential risk.
The adverse effects of emerging toxics and metabolites to plant, microorganism and human health have become research hotspots. Thus, evidence is still needed to clarify the occurrence and metabolism behavior of emerging toxics, and the risk of their transformation products should also be studied. This new evidence will guide policies to better control and manage global pollution.
This Special Issue of Toxics focuses on the distribution, metabolism and toxicity exposure of emerging toxics. Here are some examples of topics that could be addressed in this Special Issue:

1. Level and distribution of emerging toxics in the environment and organisms;
2. Migration and biotransformation of emerging toxics in animals, plants, the microbe and humans;
3. Degradation methods for toxic pollutants;
4. Biological and ecological toxicities of organic pollutants and their metabolites;
5. Metabolism and human health risks;
6. Metabolomics, proteomics and genomics.

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• emerging toxics
• environmental occurrence and fate
• migration and biotransformation
• degradation and remediation
• biological and ecological risks
• metabolism and human health