Biomonitoring Methods for Measuring Human Exposures to Consumer Products

A special issue of Toxics (ISSN 2305-6304).

Deadline for manuscript submissions: closed (30 November 2015)

Special Issue Editor


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Guest Editor
United States Environmental Protection Agency’s Center for Public Health and Environmental Assessment, Research Triangle Park, NC 27711, USA
Interests: exposure; chemicals; urinary biomonitoring; toxicology; human health

Special Issue Information

Dear Colleagues,

In the United States, over 75,000 man-made chemicals are registered for use by consumers in everyday products. These chemicals are used in a number of different types of consumer products including personal care and cleaning items, toys, food packaging, and household furnishings. It would be proactive and prudent to reduce human exposures, particularly children, to these chemicals in consumer products. Few data, however, are currently available on human exposures and potential health risks to these chemicals in consumer products using biomonitoring. Blood, urine, and exhaled breath condensate are common biological matrices used to measure for chemicals or their metabolites in humans. In this special issue, we are inviting authors to submit manuscripts that have developed new or improved biomonitoring methods for measuring human exposures to chemical(s) found in consumer products. Priority will be given to papers focusing on biomonitoring research involving children.

Dr. Marsha K. Morgan
Guest Editor

Manuscript Submission Information

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Keywords

  • exposure
  • chemicals
  • consumer products
  • biomarkers

Published Papers (1 paper)

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Research

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Article
Exposure to BPA in Children—Media-Based and Biomonitoring-Based Approaches
by Krista L.Y. Christensen and Matthew Lorber
Toxics 2014, 2(2), 134-157; https://doi.org/10.3390/toxics2020134 - 17 Apr 2014
Cited by 10 | Viewed by 6952
Abstract
Bisphenol A (BPA) is used in numerous industrial and consumer product applications resulting in ubiquitous exposure. Children’s exposure is of particular concern because of evidence of developmental effects. Childhood exposure is estimated for different age groups in two ways. The “forward” approach uses [...] Read more.
Bisphenol A (BPA) is used in numerous industrial and consumer product applications resulting in ubiquitous exposure. Children’s exposure is of particular concern because of evidence of developmental effects. Childhood exposure is estimated for different age groups in two ways. The “forward” approach uses information on BPA concentrations in food and other environmental media (air, water, etc.) combined with average contact rates for each medium. The “backward” approach relies on urinary biomonitoring, extrapolating backward to the intake which would have led to the observed biomarker level. The forward analysis shows that BPA intakes are dominated by canned food consumption, and that intakes are higher for younger ages. Mean intake estimates ranged from ~125 ng/kg-day for 1 year-olds to ~73 ng/kg-day among 16–20 years olds. Biomonitoring-based intakes show the same trend of lower intakes for older children, with an estimate of 121 (median) to 153 (mean) ng/kg-day for 2–6 years, compared with 33 (median) to 53–66 (mean) ng/kg-day for 16–20 years. Infant intakes were estimated to range from ~46 to 137 ng/kg-day. Recognizing uncertainties and limitations, this analysis suggests that the “forward” and “backward” methods provide comparable results and identify canned foods as a potentially important source of BPA exposure for children. Full article
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