Transcriptomic and Proteomic Study on Animal Venom: Looking Forward

Dear Colleagues,

Transcriptomic and proteomic studies concerning venom and venom glands constituted a major breakthrough in the characterization and knowledge of global crude venom compositions, and animal venom and venom glands in particular. More than 20 years have passed since the first studies utilized omics technologies, providing the first highthroughput data using these techniques. A critical evaluation of their contributions as well as their limitations may help to guide future research on animal venom toxin biology, with potential application in biomedical research. Novel technologies that can be combined with transcriptomic and proteomic studies are also emerging, providing new tools with the potential for a high impact in envenomation biology, evolution, therapy, the mechanisms implicated in the post-translational modification of these toxins and many other aspects. These would fill the knowledge gap at an accelerated pace. With this in mind, we will review the achievements, present contributions, gaps in the literature, integration and perspectives regarding these technologies for application in animal toxin biology and biomedical research, particularly when combined with new emerging technologies.

Dr. Paulo Lee Ho
Guest Editor

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• transcriptome
• proteome
• venom composition
• toxin(s)