Development of Therapies for Shiga Toxin
A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Bacterial Toxins".
Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 257
Special Issue Editor
Interests: glycosphingolipids(GSLs); GSL metabolism; GSL traffic; GSL function; shiga toxin; verotoxin cholera toxin; globotriaosylceramide; glucosylceramide; endoplasmic reticulum associated degradation (ERAD)
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Gastrointestinal E. coli-derived Shiga toxin (verotoxin) remains the major cause of acute pediatric renal failure—the hemolytic uremic syndrome. Despite more than 30 years of research, there is no effective treatment to prevent the pathology of toxin-induced HUS. However, recent studies have expanded the scope and knowledge of Stx-induced pathology, and have sparked novel approaches to treatment/prevention which provide hope that effective therapy is on the horizon
Prof. Dr. Clifford A. Lingwood
Guest Editor
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Keywords
- toxin subunits
- toxin family members
- glycolipid receptors
- cell carriers
- complement
- endothelial cells
- podocytes
- antibiotics
- encephalopathy
- retrograde transport
