Schistosoma japonicum and S. mekongi: The Current Situation, Advances in Biology and Epidemiology, and New Tools and Strategies in Controlling Schistosomiasis

A special issue of Tropical Medicine and Infectious Disease (ISSN 2414-6366). This special issue belongs to the section "Neglected and Emerging Tropical Diseases".

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 1451

Special Issue Editors


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Guest Editor
School of Medicine, Department of Tropical Medicine and Parasitology, Dokkyo Medical University, Tochigi, Japan
Interests: Schistosoma mekongi; Schistosoma japonicum; schistosomiasis; parasitology

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Guest Editor
Department of Life Sciences, Edward Llwyd Building, Aberystwyth University, Aberystwyth, UK
Interests: neglected tropical diseases; parasitic flatworms; schistosomiasis; functional genomics; transgenesis; genome editing; single cell transcriptomics

Special Issue Information

Dear Colleagues,

Schistosomiasis is a water-borne infectious, disease, caused by trematode parasites of the genus Schistosoma. It has caused serious problems, not only in individual health, but also in terms of socioeconomic status in endemic areas. According to the international meeting for NTDs, held by the World Health Organization (WHO), schistosomiasis has been amongst the neglected tropical diseases (NTDs) since 2005. The WHO published its second roadmap for NTDs in 2020 and set a target to achieve the elimination of schistosomiasis as a public health problem by 2030, listing the following critical actions for the elimination of schistosomiasis (WHO, 2020):

  • Define indicator for measuring morbidity.
  • Implement effective interventions, including extending preventive chemotherapy to all populations in need and ensuring access to the necessary medicines; implement targeted snail control with updated guidelines; continue micro-mapping and targeting.
  • Develop diagnostic tests, including standardized point-of-care diagnostic, and develop new interventions, including alternatives to praziquantel and methods of snail control.
  • Create effective cross-sectoral governance mechanisms to coordinate with WASH, vector control, animal health, environment and other key sectors.
  • Ensure sufficient resources, including domestic financing, for access to interventions (including MDA for children and adults as well as snail control), development of new tools and strengthening of health care capacity.

In WHO (2020): “Ending the neglect to attain the Sustainable Development Goals: a road map for neglected tropical diseases” 2021–2030. ISBN 978-92-4-001035-2 (electronic version).

This Special Issue focuses on human schistosomiasis in the western Pacific region. Cases in this region are caused by S. japonicum, distributed in the Philippines, Indonesia, and China, and S. mekongi, distributed in the Lao PDR and Cambodia. Toward the achievement of the roadmap goals, we invite the submission of articles, reviews, or short reports regarding the current situation and advances in biology and epidemiology, including our understanding of their intermediate host snails and reservoir host animals, as well as new tools and strategies in controlling schistosomiasis.

Dr. Masashi Kirinoki
Dr. Gabriel Rinaldi
Guest Editors

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Research

11 pages, 587 KiB  
Article
Trend of Human Schistosomiasis Japonica Prevalence in China from 1990 to 2019
by Yifeng Li, Tingting He, Jingzi Xie, Shangbiao Lv, Zongguang Li, Min Yuan, Fei Hu and Dandan Lin
Trop. Med. Infect. Dis. 2023, 8(7), 344; https://doi.org/10.3390/tropicalmed8070344 - 29 Jun 2023
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Abstract
Schistosomiasis (Schistosomiasis japonica) remains an important public health problem in China, and the Chinese government has set an ambitious goal of eliminating schistosomiasis by 2030. Based on the observational study of the Global Burden of Disease Study database in 2019 (GBD2019) and the [...] Read more.
Schistosomiasis (Schistosomiasis japonica) remains an important public health problem in China, and the Chinese government has set an ambitious goal of eliminating schistosomiasis by 2030. Based on the observational study of the Global Burden of Disease Study database in 2019 (GBD2019) and the World Bank database, this study aimed to analyze the prevalence trend of schistosomiasis in China from 1990 to 2019 by using the joinpoint regression model, and the relationship between economic and social development and schistosomiasis prevalence. The data of age-standardized infection rates (ASRs) from the Global Burden of Disease Study Global Health Data Exchange were collected, and Gross national product per capita (GDP) and people using safely managed sanitation services ((PPMS) % of population) were extracted from the World Bank database. Trends of ASR were analyzed using joinpoint regression analysis, the association of ASR with GDP, and PPMS using the Pearson correlation analysis. The results reveal that, from 1990 to 2019, the overall trend of ASR from schistosomiasis showed a decrease for both sexes, the decreases in men were relatively smaller compared with women. A larger decrease has been observed in the age groups from 15 to 49 years compared with other age groups. The ASR of schistosomiasis had a significant negative correlation with GDP and PPMS. This observational study identified decreasing prevalence rate of schistosomiasis in China since 1990. Continuous investment, optimization of control strategy, and economic development will help to achieve the goal of schistosomiasis elimination. Full article
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