Altholactone Displays Promising Antimicrobial Activity
Abstract
:1. Introduction
2. Results and Discussion
3. Experimental
3.1. Cell Viability Assays
3.2. Well Diffusion Assay
3.3. Determination of Minimum Inhibitory Concentration (MIC)
4. Conclusions
Acknowledgements
Conflict of Interest
References
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Sample Availability: Samples of the compounds mentioned above are available from the authors. |
Chemical | Zone of inhibition (mm) ± SE | |
---|---|---|
Altholactone (µg/mL) | S. aureus ATCC25923 | P. aeruginosa ATCC 27853 |
0 | 0 | 0 |
12.5 | 15 ± 1.5 | 0 |
25 | 24 ± 2.1 | 0 |
50 | 31 ± 2.5 | 1 ± 0 |
Ciprofloxacin (20 µg/disc) | 0 | 20 ± 1.5 |
Chloramphenicol (10 µg/mL) | 0 | 0 |
Microbe | MIC (µg/mL) |
---|---|
S. aureus ATCC25392 | 0.625 |
S. aureus ATCC25923 | 0.625 |
E. faecalis | 0.625 |
S. typhi | 1.25 |
E. coli | 1.25 |
P. aeroginosa | >15 |
C. albicans | 2.50 |
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Al Momani, F.; Alkofahi, A.S.; Mhaidat, N.M. Altholactone Displays Promising Antimicrobial Activity. Molecules 2011, 16, 4560-4566. https://doi.org/10.3390/molecules16064560
Al Momani F, Alkofahi AS, Mhaidat NM. Altholactone Displays Promising Antimicrobial Activity. Molecules. 2011; 16(6):4560-4566. https://doi.org/10.3390/molecules16064560
Chicago/Turabian StyleAl Momani, Fouad, Ahmad S. Alkofahi, and Nizar M. Mhaidat. 2011. "Altholactone Displays Promising Antimicrobial Activity" Molecules 16, no. 6: 4560-4566. https://doi.org/10.3390/molecules16064560