Cytotoxic Constituents from the Stems of Clausena lansium (Lour.) Skeels
Abstract
:1. Introduction
2. Results and Discussion
Compound | IC50 (µg/mL) a | ||||
---|---|---|---|---|---|
Hela | K562 | A549 | H1299 | SMMC-7721 | |
1 | >50 | >50 | >50 | >50 | >50 |
2 | >50 | >50 | >50 | >50 | >50 |
3 | 46.21 ± 2.61 | >50 | 46.27 ± 3.26 | >50 | 25.24 ± 1.86 |
4 | 12.71 ± 3.58 | 20.48 ± 1.76 | 37.64 ± 1.34 | 13.23 ± 2.36 | 6.19 ± 0.59 |
5 | 33.08 ± 8.92 | 26.50 ± 2.12 | 30.09 ± 1.58 | 15.77 ± 1.89 | 10.69 ± 1.83 |
6 | 29.85 ± 2.95 | 23.49 ± 1.85 | >50 | 26.84 ± 1.45 | 7.61 ± 1.49 |
DOX b | 1.52 ± 0.06 | 11.04 ± 6.81 | 2.38 ± 0.22 | 10.04 ± 0.06 | 0.77 ± 0.07 |
3. Experimental
3.1. General
3.2. Plant Material
3.3. Extraction and Isolation
3.4. Cytotoxicity Assay
4. Conclusions
Acknowledgments
Conflicts of Interest
References
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Jiang, H.Y.; Wang, C.F.; Fan, L.; Yang, K.; Feng, J.B.; Geng, Z.F.; Xu, J.; Deng, Z.W.; Du, S.S.; Yin, H.B. Cytotoxic Constituents from the Stems of Clausena lansium (Lour.) Skeels. Molecules 2013, 18, 10768-10775. https://doi.org/10.3390/molecules180910768
Jiang HY, Wang CF, Fan L, Yang K, Feng JB, Geng ZF, Xu J, Deng ZW, Du SS, Yin HB. Cytotoxic Constituents from the Stems of Clausena lansium (Lour.) Skeels. Molecules. 2013; 18(9):10768-10775. https://doi.org/10.3390/molecules180910768
Chicago/Turabian StyleJiang, Hai Yan, Cheng Fang Wang, Li Fan, Kai Yang, Jiang Bin Feng, Zhu Feng Geng, Jing Xu, Zhi Wei Deng, Shu Shan Du, and Hai Bo Yin. 2013. "Cytotoxic Constituents from the Stems of Clausena lansium (Lour.) Skeels" Molecules 18, no. 9: 10768-10775. https://doi.org/10.3390/molecules180910768
APA StyleJiang, H. Y., Wang, C. F., Fan, L., Yang, K., Feng, J. B., Geng, Z. F., Xu, J., Deng, Z. W., Du, S. S., & Yin, H. B. (2013). Cytotoxic Constituents from the Stems of Clausena lansium (Lour.) Skeels. Molecules, 18(9), 10768-10775. https://doi.org/10.3390/molecules180910768