Biotransformed Metabolites of the Hop Prenylflavanone Isoxanthohumol
Abstract
:1. Introduction
2. Results and Discussion
2.1. Preparation and Microbial Biotransformation of Isoxanthohumol
2.2. Structure Elucidation of Isoxanthohumol Metabolites
3. Materials and Methods
3.1. General Experimental Procedures
3.2. Chemicals and Ingredients
3.3. Microorganisms and Fermentation
3.4. Biotransformation Screening Procedure
3.5. Biotransformation of Isoxanthohumol (1) by R. oryzae KCTC 6399
3.6. Biotransformation of 1 by F. oxysporum f.sp. lini KCTC 16325
3.7. Determination of Absolute Configuration by Modified Mosher’s Method
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Sample Availability: Samples of the compounds are currently unavailable from the authors. |
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Kim, H.J.; Yim, S.-H.; Han, F.; Kang, B.Y.; Choi, H.J.; Jung, D.-W.; Williams, D.R.; Gustafson, K.R.; Kennelly, E.J.; Lee, I.-S. Biotransformed Metabolites of the Hop Prenylflavanone Isoxanthohumol. Molecules 2019, 24, 394. https://doi.org/10.3390/molecules24030394
Kim HJ, Yim S-H, Han F, Kang BY, Choi HJ, Jung D-W, Williams DR, Gustafson KR, Kennelly EJ, Lee I-S. Biotransformed Metabolites of the Hop Prenylflavanone Isoxanthohumol. Molecules. 2019; 24(3):394. https://doi.org/10.3390/molecules24030394
Chicago/Turabian StyleKim, Hyun Jung, Soon-Ho Yim, Fubo Han, Bok Yun Kang, Hyun Jin Choi, Da-Woon Jung, Darren R. Williams, Kirk R. Gustafson, Edward J. Kennelly, and Ik-Soo Lee. 2019. "Biotransformed Metabolites of the Hop Prenylflavanone Isoxanthohumol" Molecules 24, no. 3: 394. https://doi.org/10.3390/molecules24030394