2-Deoxyglucose-Modified Folate Derivative: Self-Assembling Nanoparticle Able to Load Cisplatin
Abstract
:1. Introduction
2. Results
2.1. Water Solubility of FA-2-DG
2.2. Intermolecular Hydrogen Bonding
2.3. Critical Micelle Concentration (CMC) of FA-2-DG
2.4. Dynamic Light Scattering (DLS) Measurement of FA-2-DG
2.5. Ability of FA-2-DG to Load Cisplatin
3. Materials and Methods
3.1. Preparation of FA-2-DG
3.2. Optical Characterization Method
3.3. DLS Characterization
3.4. Cisplatin Loading Method and Evaluation of Efficiency
4. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Sample Availability: Samples of the FA-2-DG is available from the authors. |
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Jin, S.; Du, Z.; Wang, P.; Guo, H.; Zhang, H.; Lei, X.; Ren, F. 2-Deoxyglucose-Modified Folate Derivative: Self-Assembling Nanoparticle Able to Load Cisplatin. Molecules 2019, 24, 1084. https://doi.org/10.3390/molecules24061084
Jin S, Du Z, Wang P, Guo H, Zhang H, Lei X, Ren F. 2-Deoxyglucose-Modified Folate Derivative: Self-Assembling Nanoparticle Able to Load Cisplatin. Molecules. 2019; 24(6):1084. https://doi.org/10.3390/molecules24061084
Chicago/Turabian StyleJin, Shaoming, Zhongyao Du, Pengjie Wang, Huiyuan Guo, Hao Zhang, Xingen Lei, and Fazheng Ren. 2019. "2-Deoxyglucose-Modified Folate Derivative: Self-Assembling Nanoparticle Able to Load Cisplatin" Molecules 24, no. 6: 1084. https://doi.org/10.3390/molecules24061084