Antifungal and Surface Properties of Chitosan-Salts Modified PMMA Denture Base Material
Abstract
:1. Introduction
- -
- CS-salts do not influence fungal cell growth,
- -
- the fungal cell counts on CS-salt-modified denture base material do not differ from unmodified standard material (control),
- -
- the roughness (Ra) of CS-salt-modified denture base material does not differ from unmodified standard material.
2. Results
2.1. Antifungal Test: Effect of Chitosan-Salt Solutions
2.2. Roughness
2.3. Antifungal Test: Effect of CS-Salt Modified PMMA
3. Materials and Methods
3.1. Chitosan(CS)-Salts
3.2. Preparation of CS-Salt Modified PMMA Specimens
3.3. Roughness Measurement
3.4. Antifungal Test
3.4.1. Candida Cell Suspension
3.4.2. Chitosan-Salt Solution
3.4.3. Optical Density Measurement
3.4.4. Biofilm Assay and Fungal Cell Count
3.5. Statistical Analysis
4. Discussion
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Group | Mean | SD | Median | Min | Max |
---|---|---|---|---|---|
PMMA + CS-G 0.1% | 1.79 × 104 | 1.03 × 104 | 1.90 × 104 | 1.00 × 103 | 3.50 × 104 |
PMMA + CS-G 0.3% | 4.48 × 104 | 1.00 × 105 | 1.05 × 104 | 1.00 × 103 | 2.93 × 105 |
PMMA + CS-G 1% | 1.26 × 104 | 1.89 × 104 | 3.50 × 103 *A | 2.00 × 103 | 5.70 × 104 |
PMMA + CS-G 3% | 3.76 × 105 | 1.85 × 105 | 3.41 × 105 | 1.52 × 105 | 7.20 × 105 |
PMMA + CS-HCl 0.1% | 2.83 × 104 | 3.34 × 104 | 2.00 × 104 | 8.00 × 103 | 1.10 × 105 |
PMMA + CS-HCl 0.3% | 2.88 × 104 | 1.28 × 104 | 2.90 × 104 | 8.00 × 103 | 4.60 × 104 |
PMMA + CS-HCl 1% | 1.30 × 104 | 1.04 × 104 | 1.25 × 104 * | 2.00 × 103 | 3.00 × 104 |
PMMA + CS-HCl 3% | 7.43 × 104 | 4.39 × 104 | 6.85 × 104 | 2.90 × 104 | 1.69 × 105 |
PMMA (control) | 5.08 × 104 | 4.48 × 104 | 3.85 × 104 *A | 1.00 × 104 | 1.31 × 105 |
Sample Availability: Samples of the compounds used are not available from the authors. |
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Walczak, K.; Schierz, G.; Basche, S.; Petto, C.; Boening, K.; Wieckiewicz, M. Antifungal and Surface Properties of Chitosan-Salts Modified PMMA Denture Base Material. Molecules 2020, 25, 5899. https://doi.org/10.3390/molecules25245899
Walczak K, Schierz G, Basche S, Petto C, Boening K, Wieckiewicz M. Antifungal and Surface Properties of Chitosan-Salts Modified PMMA Denture Base Material. Molecules. 2020; 25(24):5899. https://doi.org/10.3390/molecules25245899
Chicago/Turabian StyleWalczak, Katarzyna, Georg Schierz, Sabine Basche, Carola Petto, Klaus Boening, and Mieszko Wieckiewicz. 2020. "Antifungal and Surface Properties of Chitosan-Salts Modified PMMA Denture Base Material" Molecules 25, no. 24: 5899. https://doi.org/10.3390/molecules25245899