Multicomponent Reactions Involving Diazo Reagents: A 5-Year Update
Abstract
:1. Introduction
2. Reactions Based on Generation of Stable Intermediates. Other Components React to Generate a New Substrate First, Followed by Reaction with Diazo Compound
2.1. Generation of Imine/Iminium
2.2. Alkene/Alkyne-Based MCRs
2.3. MCRs Based on Generation of Other Types of Stable Intermediates
3. MCRs Where One of the Reaction Components Is a Reactive Intermediate Generated from Diazo Compound
3.1. Generation of Ylides Followed by Reaction with Carbonyl Compounds
3.2. Generation of Ylides Followed by Reaction with Imine/Iminium
3.3. Generation of Ylides Followed by Conjugate Addition Reaction
3.4. Generation of Ylides Followed by [3+2]-Cycloaddition Reactions
3.5. Generation of Ylides Followed by Other Types of Reactions
3.6. Generation of Ketene/Ketenimine
3.7. Generation of Organic Radical Species
3.8. Generation of Dearomatized Species
4. MCRs Where Reaction of Diazo Compound and One of the Components Generates a New Stable Compound, Which Further Reacts with the Third Component of the MCR
5. MCRs with In Situ Generation of Diazo Compound
6. Miscellaneous Reactions
7. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Bakulina, O.; Inyutina, A.; Dar’in, D.; Krasavin, M. Multicomponent Reactions Involving Diazo Reagents: A 5-Year Update. Molecules 2021, 26, 6563. https://doi.org/10.3390/molecules26216563
Bakulina O, Inyutina A, Dar’in D, Krasavin M. Multicomponent Reactions Involving Diazo Reagents: A 5-Year Update. Molecules. 2021; 26(21):6563. https://doi.org/10.3390/molecules26216563
Chicago/Turabian StyleBakulina, Olga, Anna Inyutina, Dmitry Dar’in, and Mikhail Krasavin. 2021. "Multicomponent Reactions Involving Diazo Reagents: A 5-Year Update" Molecules 26, no. 21: 6563. https://doi.org/10.3390/molecules26216563