Novel Chitosan-Based Schiff Base Compounds: Chemical Characterization and Antimicrobial Activity
Abstract
:1. Introduction
2. Results and Discussion
2.1. Characteristics of Chitosan-Based Schiff Base Compounds
2.2. Antimicrobial Properties of CS, CSSB-1, and CSSB-2
3. Materials and Methods
3.1. Reagents, Instruments, and Products
3.2. Bacterial Strains and Culture Conditions
3.3. Determination of the Antimicrobial Activity of CSSB
3.4. Statistical Analysis
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Sample Availability
References
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Sample | Obtained | Calculated a | Yield % | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
%C | %N | %H | C/N | %C | %N | %H | %O | % Cl | % Br | C/N | ||
Cn, DA 90.5% | 46.33 | 6.98 | 6.36 | 6.64 | 47.09 | 7.03 | 6.48 | 39.40 | - | - | 6.70 | - |
CS, DA 18.3% | 45.37 | 8.31 | 6.73 | 5.46 | 45.28 | 8.29 | 6.80 | 39.63 | - | - | 5.46 | - |
CSSB-1 | 48.13 | 7.54 | 6.37 | 6.38 | 47.92 | 7.47 | 6.59 | 35.68 | 2.35 | - | 6.41 | 17.3 |
CSSB-2 | 47.00 | 6.86 | 6.25 | 6.85 | 46.80 | 7.05 | 6.32 | 33.68 | - | 6.16 | 6.77 | 19.4 |
Vibration Type in Group and Its Wavenumber, cm−1 | |||||||
---|---|---|---|---|---|---|---|
Sample | OH; NH2 Stretch | C=N Stretch (Imine) | C-H Stretch (CH2) | C=O Stretch Amide 1 | C=C; C-H Stretch Aromatic Ring | Asymmetric Stretch C-O-C and C-N Stretch | O-bridge Stretch (Glucosamine) |
CS | 3362.5 3296.2 | - | 2874.5 | 1651.9 | - | 1150.7 1081.7 | 1028.7 |
CSSB-1 | 3367.7 3296.3 | 1639.4 | 2871.5 | - | 1602.1; 1522.1 1454.5 | 1150.4 1064.3 | 1030.1 |
CSSB-2 | 3364.6 3306.8 | 1641.0 | 2875.0 | - | 1609.2; 1518.2 1447.8 | 1150.3 1067.9 | 1025.5 |
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Fontana, R.; Marconi, P.C.R.; Caputo, A.; Gavalyan, V.B. Novel Chitosan-Based Schiff Base Compounds: Chemical Characterization and Antimicrobial Activity. Molecules 2022, 27, 2740. https://doi.org/10.3390/molecules27092740
Fontana R, Marconi PCR, Caputo A, Gavalyan VB. Novel Chitosan-Based Schiff Base Compounds: Chemical Characterization and Antimicrobial Activity. Molecules. 2022; 27(9):2740. https://doi.org/10.3390/molecules27092740
Chicago/Turabian StyleFontana, Riccardo, Peggy Carla Raffaella Marconi, Antonella Caputo, and Vasak B. Gavalyan. 2022. "Novel Chitosan-Based Schiff Base Compounds: Chemical Characterization and Antimicrobial Activity" Molecules 27, no. 9: 2740. https://doi.org/10.3390/molecules27092740