Allergens with Protease Activity from House Dust Mites
Abstract
:1. Introduction
Group 1 Allergens
2. Disruption of the Epithelial Barrier
3. Th2-Biased Immune Response
4. Reduced Th1 Polarization
5. Reduced Lung Clearance
6. Excessive IgE Production
Group 3, 6 and 9 Allergens
7. Conclusions
Acknowledgments
Conflicts of Interest
References
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Allergen Group | Identified Allergens | Protein Family | Prevalence |
---|---|---|---|
1 | Der p 1, Der f 1, Der m 1, Der s 1, Eur m 1, Blo t 1, Pso o 1, Sar s 1 | Cysteine protease, papain-like | 80% |
3 | Der p 3, Der f 3, Der s 3, Eur m 3, Blo t 3, Sar s 3, Gly d 3, Lep d 3 | Trypsin-like serine protease | 16–100% |
6 | Der p 6, Der f 6, Blo t 6 | Chymotrypsin-like serine protease | 40% |
9 | Der p 9, Der f 9, Blo t 9 | Collagenolytic-like serine protease | 90% |
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Reithofer, M.; Jahn-Schmid, B. Allergens with Protease Activity from House Dust Mites. Int. J. Mol. Sci. 2017, 18, 1368. https://doi.org/10.3390/ijms18071368
Reithofer M, Jahn-Schmid B. Allergens with Protease Activity from House Dust Mites. International Journal of Molecular Sciences. 2017; 18(7):1368. https://doi.org/10.3390/ijms18071368
Chicago/Turabian StyleReithofer, Manuel, and Beatrice Jahn-Schmid. 2017. "Allergens with Protease Activity from House Dust Mites" International Journal of Molecular Sciences 18, no. 7: 1368. https://doi.org/10.3390/ijms18071368