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Review

Novel Approaches in Ovarian Cancer Research against Heterogeneity, Late Diagnosis, Drug Resistance, and Transcoelomic Metastases

by
Anna Erol
1,*,
Magdalena Niemira
1 and
Adam Jacek Krętowski
1,2
1
Clinical Research Centre, Medical University of Białystok, M. Skłodowskiej-Curie 24a, 15-276 Białystok, Poland
2
Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, M. Skłodowskiej-Curie 24a, 15-276 Białystok, Poland
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2019, 20(11), 2649; https://doi.org/10.3390/ijms20112649
Submission received: 17 April 2019 / Revised: 27 May 2019 / Accepted: 28 May 2019 / Published: 29 May 2019
(This article belongs to the Section Molecular Oncology)
Versions Notes

Abstract

The development of modern technologies has revolutionised science and has had a huge impact on biomedical studies. This review focuses on possible tools that scientists can use to face the challenges of fighting ovarian cancer. Ovarian cancer is the deadliest gynaecologic malignancy and, even after years of study, the mortality has not decreased significantly. In the era of sequencing and personalised and precision medicine, we are now closer than ever to helping patients and physicians in regard to treatment and diagnosis of this disease. This work summarises the newest findings in the development of ovarian cancer research.
Keywords: ovarian cancer; omics; high-grade serous ovarian cancer; genomics; transcriptomics; epigenomics; metastases; cancer stem cells ovarian cancer; omics; high-grade serous ovarian cancer; genomics; transcriptomics; epigenomics; metastases; cancer stem cells

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MDPI and ACS Style

Erol, A.; Niemira, M.; Krętowski, A.J. Novel Approaches in Ovarian Cancer Research against Heterogeneity, Late Diagnosis, Drug Resistance, and Transcoelomic Metastases. Int. J. Mol. Sci. 2019, 20, 2649. https://doi.org/10.3390/ijms20112649

AMA Style

Erol A, Niemira M, Krętowski AJ. Novel Approaches in Ovarian Cancer Research against Heterogeneity, Late Diagnosis, Drug Resistance, and Transcoelomic Metastases. International Journal of Molecular Sciences. 2019; 20(11):2649. https://doi.org/10.3390/ijms20112649

Chicago/Turabian Style

Erol, Anna, Magdalena Niemira, and Adam Jacek Krętowski. 2019. "Novel Approaches in Ovarian Cancer Research against Heterogeneity, Late Diagnosis, Drug Resistance, and Transcoelomic Metastases" International Journal of Molecular Sciences 20, no. 11: 2649. https://doi.org/10.3390/ijms20112649

APA Style

Erol, A., Niemira, M., & Krętowski, A. J. (2019). Novel Approaches in Ovarian Cancer Research against Heterogeneity, Late Diagnosis, Drug Resistance, and Transcoelomic Metastases. International Journal of Molecular Sciences, 20(11), 2649. https://doi.org/10.3390/ijms20112649

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