Nanocarriers, Progenitor Cells, Combinational Approaches, and New Insights on the Retinal Therapy
Abstract
:1. Introduction
2. Gene Delivery Carriers to the Retina
2.1. Novel Gene Delivery Systems
2.2. Novel Drug Delivery Systems
2.3. Stem Cells and Their Clinical Potential for Retinal Diseases
2.4. Tissue Engineering and Nanofibrous Scaffolds for Retinal Diseases
3. Conclusions
4. Future Perspective
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Scaffolds | Components | Stem Cells |
---|---|---|
Nanofibrous scaffolds [100] | Polycaprolactone (PCL) | hRPE |
Hybrid nanofibrous scaffolds [87] | Collagen type I and poly(lactic-co-glycolic acid) (PLGA) | hRPE |
Hybrid nanofibrous scaffolds [90] | Chitosan-graft-poly(ε-caprolactone)/polycaprolactone (CS-PCL/PCL) | RPCs |
Hybrid nanofibrous scaffolds [93] | Silk fibroin, PCL, and Gelatin | iPSCs |
Hybrid nanofibrous scaffolds [92] | Laminin and Poly(epsilon-caprolactone) (PCL) | RSC |
Hybrid nanofibrous scaffolds [93] | Silk fibroin (SF) and Poly(L-lactic acid-co-ε-caprolactone) (PLCL) | RPCs |
Nanofibrous scaffold [96] | Polycaprolactone (PCL) | HCE-T |
Core-shell nanofibrous scaffolds [97] | (PEG /PCL) | CJMSCs |
Hydrogel scaffold [99] | the hydrogel of gelatin (Ge)/gellan gum (GG)/glycol chitosan (CS) | ARPE-19 |
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Pishavar, E.; Luo, H.; Bolander, J.; Atala, A.; Ramakrishna, S. Nanocarriers, Progenitor Cells, Combinational Approaches, and New Insights on the Retinal Therapy. Int. J. Mol. Sci. 2021, 22, 1776. https://doi.org/10.3390/ijms22041776
Pishavar E, Luo H, Bolander J, Atala A, Ramakrishna S. Nanocarriers, Progenitor Cells, Combinational Approaches, and New Insights on the Retinal Therapy. International Journal of Molecular Sciences. 2021; 22(4):1776. https://doi.org/10.3390/ijms22041776
Chicago/Turabian StylePishavar, Elham, Hongrong Luo, Johanna Bolander, Antony Atala, and Seeram Ramakrishna. 2021. "Nanocarriers, Progenitor Cells, Combinational Approaches, and New Insights on the Retinal Therapy" International Journal of Molecular Sciences 22, no. 4: 1776. https://doi.org/10.3390/ijms22041776