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Review
Peer-Review Record

Impact of the Exposome on the Epigenome in Inflammatory Bowel Disease Patients and Animal Models

Int. J. Mol. Sci. 2022, 23(14), 7611; https://doi.org/10.3390/ijms23147611
by Sophie Vieujean 1, Bénédicte Caron 2, Vincent Haghnejad 2, Jean-Yves Jouzeau 3, Patrick Netter 3, Anne-Charlotte Heba 4, Ndeye Coumba Ndiaye 4, David Moulin 3, Guillermo Barreto 3,5,6, Silvio Danese 7 and Laurent Peyrin-Biroulet 2,*
Reviewer 1:
Reviewer 2: Anonymous
Int. J. Mol. Sci. 2022, 23(14), 7611; https://doi.org/10.3390/ijms23147611
Submission received: 31 May 2022 / Revised: 5 July 2022 / Accepted: 6 July 2022 / Published: 9 July 2022
(This article belongs to the Special Issue Molecular Advances in Inflammatory Bowel Diseases)

Round 1

Reviewer 1 Report

This paper is well written and deeply clarifies interesting aspects in this field.

 

Author Response

Dear reviewer 1,

Thank you for your time in reviewing this manuscript, for your positive feedback and for allowing us to submit a revised version of our manuscript. We did a proofreading to correct some English mistakes. 

Thank you again, 

Best regards

Sophie Vieujean

Reviewer 2 Report

The current review article entitled “Impact of the exposome on the epigenome of inflammatory bowel disease patients” by Vieujean et al. discussed in depth about the effects of environmental exposures on intestinal inflammation. Authors wrote this review article elegantly and also summarized the literature in the form of tables.

Minor comment

1.     As authors discussed impact of various factors of environment on intestinal inflammation and cited literature for both mouse and human studies. However, in title of  the review is “inflammatory bowel disease (IBD) patients” which is misleading. It should be for example in animal models of IBD and IBD patients.

Author Response

Dear reviewer 2,

Thank you for your time in reviewing this manuscript, for your positive feedback and for allowing us to submit a revised version of our manuscript. We agree with your comment on the title and it has therefore been changed. We did a proofreading to correct some English mistakes. 

Thank you again, 

Best regards, 

Sophie Vieujean

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