The Asparaginyl Endopeptidase Legumain: An Emerging Therapeutic Target and Potential Biomarker for Alzheimer’s Disease
Round 1
Reviewer 1 Report
Minor revision
Comments for author File: Comments.pdf
Author Response
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Author Response File: Author Response.pdf
Reviewer 2 Report
The manuscript reviews the overactivation of asparaginyl endopeptidase (AEP) in different neuropathological processes of Alzheimer's disease (AD). The manuscript is interesting, well written and updated. Since late events of AD are characterized by neuronal death, the authors should also investigate the potential role of AEP in neuronal death processes. This information can stimulate the study and development of new neuroprotective drugs for AD.
Author Response
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Author Response File: Author Response.pdf