Adaptive Synthesis of Functional Amphiphilic Dendrons as a Novel Approach to Artificial Supramolecular Objects
Abstract
:1. Introduction
2. Results and Discussion
2.1. Synthesis and Characterization of Carbosilane Amphiphilic Dendrons
2.2. Dynamic Light Scattering and Zeta Potential
2.3. Computational Study
3. Materials and Methods
3.1. General Remarks
3.2. Dynamic Light Scattering (DLS)
3.3. Computational Study
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Amphiphilic Structure | Size (nm) | Zeta Potential 1 (mV) | ||||||
---|---|---|---|---|---|---|---|---|
0.1 (µM) | 0.5 (µM) | 1 (µM) | 5 (µM) | 10 (µM) | 50 (µM) | 100 (µM) | ||
L1–9 | 69 ± 13 | 55 ± 5 | 52 ± 4 | 47 ± 18 | 28 ± 2 | 8 ± 1 | 8 ± 1 | 39.3 ± 3.0 |
L2–12 | 124 ± 2 | 76 ± 34 | 25 ± 19 | 13 ± 2 | 36 ± 2 | 24 ± 18 | 7 ± 1 | 71.5 ± 3.5 |
L2–15a | 78 ± 27 | 75 ± 5 | 104 ± 1 | 68 ± 8 | 73 ± 4 | 60 ± 7 | 70 ± 1 | 62.7 ± 7.0 |
L2–15b | 20 ± 4 | 20 ± 8 | 20 ± 6 | 25 ± 4 | 23 ± 3 | 25 ± 4 | 28 ± 5 | 68.5 ± 0.5 |
L2–19a | 17 ± 4 | 18 ± 6 | 31 ± 47 | 36 ± 29 | 67 ± 37 | 79 ± 9 | 63 ± 11 | 71.7 ± 1.6 |
L2–19b | 6 ± 7 | 3 ± 1 | 7 ± 3 | 7 ± 4 | 6 ± 2 | 7 ± 2 | 7 ± 1 | 52.8 ± 8.6 |
L1–8 | 6 ± 2 | 7 ± 1 | 5 ± 3 | 7 ± 1 | 7 ± 4 | 7 ± 2 | 6 ± 2 | −27.2 ± 3.9 |
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Edr, A.; Wrobel, D.; Krupková, A.; Šťastná, L.Č.; Cuřínová, P.; Novák, A.; Malý, J.; Kalasová, J.; Malý, J.; Malý, M.; et al. Adaptive Synthesis of Functional Amphiphilic Dendrons as a Novel Approach to Artificial Supramolecular Objects. Int. J. Mol. Sci. 2022, 23, 2114. https://doi.org/10.3390/ijms23042114
Edr A, Wrobel D, Krupková A, Šťastná LČ, Cuřínová P, Novák A, Malý J, Kalasová J, Malý J, Malý M, et al. Adaptive Synthesis of Functional Amphiphilic Dendrons as a Novel Approach to Artificial Supramolecular Objects. International Journal of Molecular Sciences. 2022; 23(4):2114. https://doi.org/10.3390/ijms23042114
Chicago/Turabian StyleEdr, Antonín, Dominika Wrobel, Alena Krupková, Lucie Červenková Šťastná, Petra Cuřínová, Aleš Novák, Jan Malý, Jitka Kalasová, Jan Malý, Marek Malý, and et al. 2022. "Adaptive Synthesis of Functional Amphiphilic Dendrons as a Novel Approach to Artificial Supramolecular Objects" International Journal of Molecular Sciences 23, no. 4: 2114. https://doi.org/10.3390/ijms23042114