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Cancer as a Metabolic Disorder
 
 
Review
Peer-Review Record

Fatty Acid Metabolism in Ovarian Cancer: Therapeutic Implications

Int. J. Mol. Sci. 2022, 23(4), 2170; https://doi.org/10.3390/ijms23042170
by Hyunho Yoon 1 and Sanghoon Lee 2,*
Reviewer 1:
Reviewer 2: Anonymous
Int. J. Mol. Sci. 2022, 23(4), 2170; https://doi.org/10.3390/ijms23042170
Submission received: 29 January 2022 / Revised: 15 February 2022 / Accepted: 15 February 2022 / Published: 16 February 2022
(This article belongs to the Special Issue Advances in Cancer Metabolism and Tumour Microenvironment 2.0)

Round 1

Reviewer 1 Report

This review article by Yoon et al, is well written, brings many excellent pints, short, sweet and to the point. I would love to recommend this work. I have a few suggestions to the authors which can improve the present MS.

> Role of Fatty acid transport proteins, scavenger proteins such as CD36 have not been mentioned. 

>Explaining role of fatty acid metabolism in different types of ovarian cancer pathogenesis can add value to present MS.

> What is the role of unregulated fatty acid metabolism in adaptive immune responses such as Tcell subsets?

> Please incorporate more in depth mechanism of action on the role of fatty acid metabolism in ovarian cancer cell proliferation, metastasis and ovarian tumor micro environment regulation.

 

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

Dear authors, I would like to congratulate you on a meticulously prepared manuscript, which presents a detailed overview of knowledge based on current literature data. The article is presented in a legible and understandable way for the reader.

Author Response

We appreciate your review and comments.

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