Peer-Review Record
HNF1A Mutations and Beta Cell Dysfunction in Diabetes
Int. J. Mol. Sci. 2022, 23(6), 3222; https://doi.org/10.3390/ijms23063222
Reviewer 1:
Anonymous
Reviewer 2:
Anonymous
Int. J. Mol. Sci. 2022, 23(6), 3222; https://doi.org/10.3390/ijms23063222
Submission received: 28 February 2022
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Revised: 14 March 2022
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Accepted: 16 March 2022
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Published: 16 March 2022
(This article belongs to the Special Issue Fate of Pancreatic Islets in Type 2 Diabetes)
Round 1
Reviewer 1 Report
This review is updated summary HNF1A genetics and pathophysiology. This manuscript can be accepted with minor revise.
- The authors add more information about HNF1A protein such as its domain and binding partner at different tissue.
- In line 62, HNA1A should be HNF1A.
Author Response
Please see the attachment.
Author Response File: 
Author Response.pdf
Reviewer 2 Report
This is a review article regarding HNF1A mutations and beta cell dysfunction in diabetes. Overall, the manuscript was concisely and well written. The topic is of interest and informative. There are some comments.
- The authors discuss the similarities and differences in the role of HNF1A mutations between MODY3 and T2DM. It will be better if the authors summarize them in a table.
- It will be better if the authors summarize perspectives on future research direction in a table.
Author Response
Please see the attachment.
Author Response File: Author Response.pdf
