Convergent Genomic Signatures of Cashmere Traits: Evidence for Natural and Artificial Selection
Abstract
:1. Introduction
2. Results
2.1. Genetic Evolution under Natural Selection Pressure
2.2. Signals of Convergent Evolution between Tibetan Antelope and Siberian Ibex
2.3. Candidate Artificial Selection Genes Screening and Enrichment Analysis of Cashmere Traits
2.4. Identification of Key Gene Modules and Differentially Expressed Genes Related to Cashmere Growth and Development
2.5. Co-Regulatory Network of Cashmere Traits
3. Discussion
4. Materials and Methods
4.1. Species Selection and Data Collection
4.2. Phylogenetic Tree and Multiple Sequence Alignment
4.3. Analysis of Positively Selected Genes and Rapidly Evolving Genes
4.4. Identification of Convergent Amino Acid Substitutions
4.5. Reads Alignment and SNP Calling
4.6. Genome-Wide Selective Sweep Test
4.7. RNA Sequencing Data Analysis
4.8. Construction of Weighted Gene Coexpression Network
4.9. Identification of Significant Modules and Key Genes Related to Hair Follicle Development
4.10. Gene Enrichment Analysis
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Wang, W.; Li, Z.; Xie, G.; Li, X.; Wu, Z.; Li, M.; Liu, A.; Xiong, Y.; Wang, Y. Convergent Genomic Signatures of Cashmere Traits: Evidence for Natural and Artificial Selection. Int. J. Mol. Sci. 2023, 24, 1165. https://doi.org/10.3390/ijms24021165
Wang W, Li Z, Xie G, Li X, Wu Z, Li M, Liu A, Xiong Y, Wang Y. Convergent Genomic Signatures of Cashmere Traits: Evidence for Natural and Artificial Selection. International Journal of Molecular Sciences. 2023; 24(2):1165. https://doi.org/10.3390/ijms24021165
Chicago/Turabian StyleWang, Wei, Zhuohui Li, Guoxiang Xie, Xinmei Li, Zhipei Wu, Manman Li, Anguo Liu, Yan Xiong, and Yu Wang. 2023. "Convergent Genomic Signatures of Cashmere Traits: Evidence for Natural and Artificial Selection" International Journal of Molecular Sciences 24, no. 2: 1165. https://doi.org/10.3390/ijms24021165