An Insight into the Impact of Serum Tellurium, Thallium, Osmium and Antimony on the Antioxidant/Redox Status of PCOS Patients: A Comprehensive Study
Abstract
:1. Introduction
2. Results
3. Discussion
4. Materials and Methods
4.1. Ethical Approval and Study Design
4.2. Collection of Sample and Measurement of Baseline Characteristics
4.3. Serum Te, TI, Os, and Sb Determination
4.4. Assessment of Antioxidant/Redox Status in Serum
4.4.1. Superoxide Dismutase (SOD), Catalase (CAT), Superoxide Anion (SOA), and Hydrogen Peroxide (H2O2)
4.4.2. Lipid Peroxidation (LPO) and Protein Carbonylation (PCC)
4.4.3. Glutathione Status
4.5. Statistical Analysis
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Control | PCOS | p | |
---|---|---|---|
Age | 29.16 ± 6.2 | 30.41 ± 6.8 | NS |
BMI | 25.0 ± 6.08 | 27.23 ± 5.0 | NS |
Married | 30 | 24 | |
Thallium (ppb) | 1.41 ± 0.4 | 12.69 ± 1.05 | <0.001 |
Tellurium (ppb) | 1.32 ± 0.46 | 12.33 ± 1.31 | <0.001 |
Osmium (ppb) | 1.51 ± 0.45 | 13.0 ± 0.97 | <0.001 |
Antimony (ppb) | 1.89 ± 0.31 | 2.50 ± 0.23 | <0.001 |
TAC (µmol/L) | 687.00 ± 11.80 | 640.00 ± 22.0 | <0.001 |
Te-PCOS r (p) | TI-PCOS r (p) | Sb-PCOS r (p) | Os-PCOS r (p) | |
---|---|---|---|---|
TAC-PCOS | −0.132 (0.036) * | −0.210 (0.014) * | −0.142 (0.032) * | −0.194 (0.01) * |
Te-PCOS | 0.49 (<0.001) ** | 0.53 (<0.0001) *** | 0.480 (<0.001) ** | |
TI-PCOS | 0.72 (<0.0001) *** | 0.71 (NS) | ||
Sb-PCOS | 0.53 (<0.001) ** |
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Abudawood, M.; Alnuaim, L.; Tabassum, H.; Ghneim, H.K.; Alfhili, M.A.; Alanazi, S.T.; Alenzi, N.D.; Alsobaie, S. An Insight into the Impact of Serum Tellurium, Thallium, Osmium and Antimony on the Antioxidant/Redox Status of PCOS Patients: A Comprehensive Study. Int. J. Mol. Sci. 2023, 24, 2596. https://doi.org/10.3390/ijms24032596
Abudawood M, Alnuaim L, Tabassum H, Ghneim HK, Alfhili MA, Alanazi ST, Alenzi ND, Alsobaie S. An Insight into the Impact of Serum Tellurium, Thallium, Osmium and Antimony on the Antioxidant/Redox Status of PCOS Patients: A Comprehensive Study. International Journal of Molecular Sciences. 2023; 24(3):2596. https://doi.org/10.3390/ijms24032596
Chicago/Turabian StyleAbudawood, Manal, Lulu Alnuaim, Hajera Tabassum, Hazem K. Ghneim, Mohammad A. Alfhili, Samyah T. Alanazi, Naif D. Alenzi, and Sarah Alsobaie. 2023. "An Insight into the Impact of Serum Tellurium, Thallium, Osmium and Antimony on the Antioxidant/Redox Status of PCOS Patients: A Comprehensive Study" International Journal of Molecular Sciences 24, no. 3: 2596. https://doi.org/10.3390/ijms24032596