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Open AccessReview
Polynucleotides in Aesthetic Medicine: A Review of Current Practices and Perceived Effectiveness
by
Kar Wai Alvin Lee
Kar Wai Alvin Lee 1,
Kwin Wah Lisa Chan
Kwin Wah Lisa Chan 1,
Angela Lee
Angela Lee 2,
Cheuk Hung Lee
Cheuk Hung Lee 1,
Jovian Wan
Jovian Wan 3
,
Sky Wong
Sky Wong 4
and
Kyu-Ho Yi
Kyu-Ho Yi 5,6,*
1
EverKeen Medical Centre, Hong Kong
2
The Skin Oracle, Hong Kong
3
Asia-Pacific Aesthetic Academy, Hong Kong
4
Leciel Medical Centre, Hong Kong
5
Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea
6
Maylin Clinic (Apgujeong), Seoul, Republic of Korea
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2024, 25(15), 8224; https://doi.org/10.3390/ijms25158224 (registering DOI)
Submission received: 8 July 2024
/
Revised: 23 July 2024
/
Accepted: 25 July 2024
/
Published: 27 July 2024
Abstract
Polynucleotides, complex molecules composed of nucleotides, have gained attention in aesthetic medicine for their potential to regulate gene expression and promote tissue regeneration. This review aims to provide an overview of the current practices and perceived effectiveness of polynucleotides in aesthetic medicine. A comprehensive search of the literature was conducted using keywords related to polynucleotides, cosmetic application, and aesthetic application. Studies were selected based on their relevance to aesthetic medicine and the inclusion of human subjects. The review found that polynucleotides have been used to improve skin texture, reduce wrinkle depth, and enhance facial appearance. The studies reported varying degrees of efficacy and safety, with some studies demonstrating significant improvements in skin elasticity and hydration. However, others reported limited or no benefits. The review also highlighted the need for further research to establish the optimal use and efficacy of polynucleotides in aesthetic medicine. While the existing literature suggests that polynucleotides may have potential benefits in aesthetic medicine, more research is needed to fully understand their mechanisms of action and optimal use. Clinicians should be aware of the current limitations and potential risks associated with the use of polynucleotides in aesthetic medicine.
Share and Cite
MDPI and ACS Style
Lee, K.W.A.; Chan, K.W.L.; Lee, A.; Lee, C.H.; Wan, J.; Wong, S.; Yi, K.-H.
Polynucleotides in Aesthetic Medicine: A Review of Current Practices and Perceived Effectiveness. Int. J. Mol. Sci. 2024, 25, 8224.
https://doi.org/10.3390/ijms25158224
AMA Style
Lee KWA, Chan KWL, Lee A, Lee CH, Wan J, Wong S, Yi K-H.
Polynucleotides in Aesthetic Medicine: A Review of Current Practices and Perceived Effectiveness. International Journal of Molecular Sciences. 2024; 25(15):8224.
https://doi.org/10.3390/ijms25158224
Chicago/Turabian Style
Lee, Kar Wai Alvin, Kwin Wah Lisa Chan, Angela Lee, Cheuk Hung Lee, Jovian Wan, Sky Wong, and Kyu-Ho Yi.
2024. "Polynucleotides in Aesthetic Medicine: A Review of Current Practices and Perceived Effectiveness" International Journal of Molecular Sciences 25, no. 15: 8224.
https://doi.org/10.3390/ijms25158224
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