The Role of Natural Products in Immunopharmacology
Conflicts of Interest
References
- Scicchitano, S.; Vecchio, E.; Battaglia, A.M.; Oliverio, M.; Nardi, M.; Procopio, A.; Costanzo, F.; Biamonte, F.; Faniello, M.C. The Double-Edged Sword of Oleuropein in Ovarian Cancer Cells: From Antioxidant Functions to Cytotoxic Effects. Int. J. Mol. Sci. 2023, 24, 842. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Antoniou, C.; Hull, J. The Anti-cancer Effect of Olea europaea L. Products: A Review. Curr. Nutr. Rep. 2021, 10, 99–124. [Google Scholar] [CrossRef] [PubMed]
- Rishmawi, S.; Haddad, F.; Dokmak, G.; Karaman, R. A Comprehensive Review on the Anti-Cancer Effects of Oleuropein. Life 2022, 12, 1140. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Jędrzejewski, T.; Pawlikowska, M.; Sobocińska, J.; Wrotek, S. COVID-19 and Cancer Diseases-The Potential of Coriolus versicolor Mushroom to Combat Global Health Challenges. Int. J. Mol. Sci. 2023, 24, 4864. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Pilkington, K.; Wieland, L.S.; Teng, L.; Jin, X.Y.; Storey, D.; Liu, J.P. Coriolus (Trametes) versicolor mushroom to reduce adverse effects from chemotherapy or radiotherapy in people with colorectal cancer. Cochrane Database Syst. Rev. 2022, 11, CD012053. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Pojero, F.; Aiello, A.; Gervasi, F.; Caruso, C.; Ligotti, M.E.; Calabrò, A.; Procopio, A.; Candore, G.; Accardi, G.; Allegra, M. Effects of Oleuropein and Hydroxytyrosol on Inflammatory Mediators: Consequences on Inflammaging. Int. J. Mol. Sci. 2022, 24, 380. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Robles-Almazan, M.; Pulido-Moran, M.; Moreno-Fernandez, J.; Ramirez-Tortosa, C.; Rodriguez-Garcia, C.; Quiles, J.L.; Ramirez-Tortosa, M. Hydroxytyrosol: Bioavailability, toxicity, and clinical applications. Food Res Int. 2018, 105, 654–667. [Google Scholar] [CrossRef] [PubMed]
- Alemán-Jiménez, C.; Domínguez-Perles, R.; Medina, S.; Prgomet, I.; López-González, I.; Simonelli-Muñoz, A.; Campillo-Cano, M.; Auñón, D.; Ferreres, F.; Gil-Izquierdo, Á. Pharmacokinetics and bioavailability of hydroxytyrosol are dependent on the food matrix in humans. Eur. J. Nutr. 2021, 60, 905–915. [Google Scholar] [CrossRef] [PubMed]
- Granados-Principal, S.; Quiles, J.L.; Ramirez-Tortosa, C.L.; Sanchez-Rovira, P.; Ramirez-Tortosa, M.C. Hydroxytyrosol: From laboratory investigations to future clinical trials. Nutr. Rev. 2010, 68, 191–206. [Google Scholar] [CrossRef] [PubMed]
- Roszczyk, A.; Turło, J.; Zagożdżon, R.; Kaleta, B. Immunomodulatory Properties of Polysaccharides from Lentinula edodes. Int. J. Mol. Sci. 2022, 23, 8980. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Calabrò, A.; Accardi, G.; Aiello, A.; Caruso, C.; Galimberti, D.; Candore, G. Senotherapeutics to Counteract Senescent Cells Are Prominent Topics in the Context of Anti-Ageing Strategies. Int. J. Mol. Sci. 2024, 25, 1792. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Pojero, F.; Gervasi, F.; Fiore, S.D.; Aiello, A.; Bonacci, S.; Caldarella, R.; Attanzio, A.; Candore, G.; Caruso, C.; Ligotti, M.E.; et al. Anti-Inflammatory Effects of Nutritionally Relevant Concentrations of Oleuropein and Hydroxytyrosol on Peripheral Blood Mononuclear Cells: An Age-Related Analysis. Int. J. Mol. Sci. 2023, 24, 11029. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Altomare, R.; Damiano, G.; Palumbo, V.D.; Buscemi, S.; Spinelli, G.; Cacciabaudo, F.; Fazzotta, S.; Gulotta, E.; Maione, C.; Lo Monte, A.I. Feeding the brain: The importance of nutrients for brain functions and health. Prog. Nutr. 2017, 19, 243–247. [Google Scholar] [CrossRef]
- Aiello, A.; Farzaneh, F.; Candore, G.; Caruso, C.; Davinelli, S.; Gambino, C.M.; Ligotti, M.E.; Zareian, N.; Accardi, G. Immunosenescence and Its Hallmarks: How to Oppose Aging Strategically? A Review of Potential Options for Therapeutic Intervention. Front. Immunol. 2019, 10, 2247. [Google Scholar] [CrossRef] [PubMed]
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Share and Cite
Accardi, G.; Di Majo, D.; Aiello, A. The Role of Natural Products in Immunopharmacology. Int. J. Mol. Sci. 2024, 25, 9256. https://doi.org/10.3390/ijms25179256
Accardi G, Di Majo D, Aiello A. The Role of Natural Products in Immunopharmacology. International Journal of Molecular Sciences. 2024; 25(17):9256. https://doi.org/10.3390/ijms25179256
Chicago/Turabian StyleAccardi, Giulia, Danila Di Majo, and Anna Aiello. 2024. "The Role of Natural Products in Immunopharmacology" International Journal of Molecular Sciences 25, no. 17: 9256. https://doi.org/10.3390/ijms25179256