A Novel Fabrication of Heterogeneous Saponified Poly(Vinyl Alcohol)/Pullulan Blend Film for Improved Wound Healing Application
Abstract
:1. Introduction
2. Results and Discussion
2.1. OM
2.2. SEM
2.3. AFM
2.4. FT-IR Spectroscopy
2.5. XRD
2.6. 1H-NMR Spectroscopy
2.7. Contact Angle Analysis
2.8. TGA
2.9. Stress–Strain Curves
2.10. Wound-Healing Properties of Saponified PVAc/PULL Film
3. Materials and Methods
3.1. Materials
3.2. Fabrication of PVAc/PULL Blend Film and Heterogenous Saponified PVA/PULL Film
3.3. Mechanical Properties
3.4. Characterization
3.5. Assessment of In Vivo Wound-Healing Efficiency
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Samples | Weight (mg) | Thickness (µm) | Contact Angle (°) |
---|---|---|---|
PVAc film | 88 ± 7 | 80 ± 9 | 85.96 ± 1.76 |
Saponified PVAc film | 39 ± 9 | 90 ± 6 | 13.13 ± 0.65 |
PVAc/PULL 90/10 film | 90 ± 5 | 130 ± 15 | 81.67 ± 1.98 |
Saponified PVAc/PULL 90/10 film | 62.3 ± 6 | 90 ± 9 | 6.73 ± 0. 66 |
PVAc/PULL 80/20 film | 97 ± 16 | 140 ± 18 | 62.79 ± 1.44 |
Saponified PVAc/PULL 80/20 film | 58.4 ± 8 | 97 ±11 | 4.4 ± 0.44 |
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Yeasmin, S.; Jung, J.H.; Lee, J.; Kim, T.Y.; Yang, S.B.; Kwon, D.-J.; Kim, M.O.; Yeum, J.H. A Novel Fabrication of Heterogeneous Saponified Poly(Vinyl Alcohol)/Pullulan Blend Film for Improved Wound Healing Application. Int. J. Mol. Sci. 2024, 25, 1026. https://doi.org/10.3390/ijms25021026
Yeasmin S, Jung JH, Lee J, Kim TY, Yang SB, Kwon D-J, Kim MO, Yeum JH. A Novel Fabrication of Heterogeneous Saponified Poly(Vinyl Alcohol)/Pullulan Blend Film for Improved Wound Healing Application. International Journal of Molecular Sciences. 2024; 25(2):1026. https://doi.org/10.3390/ijms25021026
Chicago/Turabian StyleYeasmin, Sabina, Jae Hoon Jung, Jungeon Lee, Tae Young Kim, Seong Baek Yang, Dong-Jun Kwon, Myoung Ok Kim, and Jeong Hyun Yeum. 2024. "A Novel Fabrication of Heterogeneous Saponified Poly(Vinyl Alcohol)/Pullulan Blend Film for Improved Wound Healing Application" International Journal of Molecular Sciences 25, no. 2: 1026. https://doi.org/10.3390/ijms25021026