Ferroptosis, a Regulated Form of Cell Death, as a Target for the Development of Novel Drugs Preventing Ischemia/Reperfusion of Cardiac Injury, Cardiomyopathy and Stress-Induced Cardiac Injury
Abstract
:1. Introduction
2. The Main Manifestation of Ferroptosis
3. Inhibitors of Ferroptosis
4. The Role of Kinases in the Regulation of Ferroptosis
5. The Role of Non-Coding RNA in the Regulation of Ferroptosis in the Heart
6. The Role of Transcription Factors in the Regulation of Ferroptosis
7. Inflammation
8. Ischemia/Reperfusion of Cardiac Injury
9. Chemotherapeutic Agent-Induced Cardiomyopathy
10. Septic Cardiomyopathy
11. Diabetic Cardiomyopathy
12. Stress-Induced Cardiac Injury
13. Unresolved Issues and Prospects for the Use of Ferroptosis Inhibitors for the Treatment of Cardiovascular Diseases
14. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Ryabov, V.V.; Maslov, L.N.; Vyshlov, E.V.; Mukhomedzyanov, A.V.; Kilin, M.; Gusakova, S.V.; Gombozhapova, A.E.; Panteleev, O.O. Ferroptosis, a Regulated Form of Cell Death, as a Target for the Development of Novel Drugs Preventing Ischemia/Reperfusion of Cardiac Injury, Cardiomyopathy and Stress-Induced Cardiac Injury. Int. J. Mol. Sci. 2024, 25, 897. https://doi.org/10.3390/ijms25020897
Ryabov VV, Maslov LN, Vyshlov EV, Mukhomedzyanov AV, Kilin M, Gusakova SV, Gombozhapova AE, Panteleev OO. Ferroptosis, a Regulated Form of Cell Death, as a Target for the Development of Novel Drugs Preventing Ischemia/Reperfusion of Cardiac Injury, Cardiomyopathy and Stress-Induced Cardiac Injury. International Journal of Molecular Sciences. 2024; 25(2):897. https://doi.org/10.3390/ijms25020897
Chicago/Turabian StyleRyabov, Vyacheslav V., Leonid N. Maslov, Evgeniy V. Vyshlov, Alexander V. Mukhomedzyanov, Mikhail Kilin, Svetlana V. Gusakova, Alexandra E. Gombozhapova, and Oleg O. Panteleev. 2024. "Ferroptosis, a Regulated Form of Cell Death, as a Target for the Development of Novel Drugs Preventing Ischemia/Reperfusion of Cardiac Injury, Cardiomyopathy and Stress-Induced Cardiac Injury" International Journal of Molecular Sciences 25, no. 2: 897. https://doi.org/10.3390/ijms25020897