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Volume 17
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Review

Biosensing Using Magnetic Particle Detection Techniques

by
Yi-Ting Chen
,
Arati G. Kolhatkar
,
Oussama Zenasni
,
Shoujun Xu
* and
T. Randall Lee
*
Department of Chemistry and the Texas Center for Superconductivity, University of Houston, Houston, TX 77204, USA
*
Authors to whom correspondence should be addressed.
Sensors 2017, 17(10), 2300; https://doi.org/10.3390/s17102300
Submission received: 2 July 2017 / Revised: 26 August 2017 / Accepted: 30 August 2017 / Published: 10 October 2017
(This article belongs to the Special Issue GMR and TMR Sensors)
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Abstract

Magnetic particles are widely used as signal labels in a variety of biological sensing applications, such as molecular detection and related strategies that rely on ligand-receptor binding. In this review, we explore the fundamental concepts involved in designing magnetic particles for biosensing applications and the techniques used to detect them. First, we briefly describe the magnetic properties that are important for bio-sensing applications and highlight the associated key parameters (such as the starting materials, size, functionalization methods, and bio-conjugation strategies). Subsequently, we focus on magnetic sensing applications that utilize several types of magnetic detection techniques: spintronic sensors, nuclear magnetic resonance (NMR) sensors, superconducting quantum interference devices (SQUIDs), sensors based on the atomic magnetometer (AM), and others. From the studies reported, we note that the size of the MPs is one of the most important factors in choosing a sensing technique.
Keywords: magnetic particles; spintronic sensors; GMR; NMR; SQUID; atomic magnetometer; molecular sensing magnetic particles; spintronic sensors; GMR; NMR; SQUID; atomic magnetometer; molecular sensing
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MDPI and ACS Style

Chen, Y.-T.; Kolhatkar, A.G.; Zenasni, O.; Xu, S.; Lee, T.R. Biosensing Using Magnetic Particle Detection Techniques. Sensors 2017, 17, 2300. https://doi.org/10.3390/s17102300

AMA Style

Chen Y-T, Kolhatkar AG, Zenasni O, Xu S, Lee TR. Biosensing Using Magnetic Particle Detection Techniques. Sensors. 2017; 17(10):2300. https://doi.org/10.3390/s17102300

Chicago/Turabian Style

Chen, Yi-Ting, Arati G. Kolhatkar, Oussama Zenasni, Shoujun Xu, and T. Randall Lee. 2017. "Biosensing Using Magnetic Particle Detection Techniques" Sensors 17, no. 10: 2300. https://doi.org/10.3390/s17102300

APA Style

Chen, Y.-T., Kolhatkar, A. G., Zenasni, O., Xu, S., & Lee, T. R. (2017). Biosensing Using Magnetic Particle Detection Techniques. Sensors, 17(10), 2300. https://doi.org/10.3390/s17102300

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