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Systematic Review
Peer-Review Record

Clinical Impact of Electronic Monitoring Devices of Inhalers in Adults with Asthma or COPD: A Systematic Review and Meta-Analysis

Pharmaceuticals 2023, 16(3), 414; https://doi.org/10.3390/ph16030414
by Noe Garin 1,2,3,*,†, Borja Zarate-Tamames 1,4,†, Laura Gras-Martin 1, Raimon Milà 2, Astrid Crespo-Lessmann 5, Elena Curto 5, Marta Hernandez 2, Conxita Mestres 2 and Vicente Plaza 5
Reviewer 1:
Reviewer 2: Anonymous
Pharmaceuticals 2023, 16(3), 414; https://doi.org/10.3390/ph16030414
Submission received: 8 February 2023 / Revised: 1 March 2023 / Accepted: 2 March 2023 / Published: 8 March 2023

Round 1

Reviewer 1 Report

Garin and Zarate-Tamames presented a systematic review and meta-analysis where they looked at the impact of clinical electronic monitoring devices. They show that the adherence in the EMD-group is favourable, and they found improved ACT scores while other outcomes demonstrated mixed results. Highlighting the benefit of EMD in optimising inhaler adherence.

I do not have specific comments but want to authors complement on the study. The manuscript is well written and reads quite well. The methodology is sound and extensive, and the discussion is interesting and great to see a limitations paragraph.

 

Figure 4 is mislabelled, instead 4a and 4b it reads 3a and 3b

Author Response

We thank the reviewer for their comments.

We change the wording in figure 4 to ensure is appropriate.

Reviewer 2 Report

Garin and the authors provided an interesting manuscript regarding electronic monitoring devices of inhalers in patients with asthma or chronic obstructive pulmonary disease. Unfortunately, these conditions are more and more frequent (especially in some parts of Europe) due to air pollution. This article is suitable for publication, just some minor technical issues:

When authors mention (within the text) a figure or table (for example figure/Figure 1…), make sure that the capital letter is unique (upper/lower case to be consistent); please go through the manuscript and check if all the abbreviations are explained properly when first time mentioned (figure/table legends doesn’t count) and check tables and make sure that the capital letter is unique (upper/lower case to be consistent) for all terms mentioned (for example asthma/Asthma…).

Author Response

We thank the reviewer for their comments.

We have “unified” the upper/lower case wording in the text and the tables. We also have checked the text and make changes to ensure all the abbreviations are explained properly when first mentioned.

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