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Review

The Roles of Moonlighting Proteins in Bacteria

1
State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China
2
School of Food Science and Technology, Jiangnan University, Wuxi 214122, China
*
Authors to whom correspondence should be addressed.
Curr. Issues Mol. Biol. 2014, 16(1), 15-22; https://doi.org/10.21775/cimb.016.015
Submission received: 12 March 2013 / Accepted: 7 May 2013 / Published: 22 July 2013

Abstract

Moonlighting proteins, characterized by their multiple autonomous functions, have been detected in bacteria. Surprisingly, many of these proteins are conserved and involved in metabolic pathway or the cell stress response. They localise to the bacterial surface to take on additional activities, which have been hypothesised to contribute to bacterial virulence or bacterial benefit. In this review, we compare the functions of moonlighting proteins in bacteria, describe the structural basis of moonlighting functions, and summarise the regulation of secretion and localisation of moonlighting proteins.

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MDPI and ACS Style

Wang, G.; Xia, Y.; Cui, J.; Gu, Z.; Song, Y.; Chen, Y.Q.; Chen, H.; Zhang, H.; Chen, W. The Roles of Moonlighting Proteins in Bacteria. Curr. Issues Mol. Biol. 2014, 16, 15-22. https://doi.org/10.21775/cimb.016.015

AMA Style

Wang G, Xia Y, Cui J, Gu Z, Song Y, Chen YQ, Chen H, Zhang H, Chen W. The Roles of Moonlighting Proteins in Bacteria. Current Issues in Molecular Biology. 2014; 16(1):15-22. https://doi.org/10.21775/cimb.016.015

Chicago/Turabian Style

Wang, Guangqiang, Yu Xia, Jing Cui, Zhennan Gu, Yuanda Song, Yong Q. Chen, Haiqin Chen, Hao Zhang, and Wei Chen. 2014. "The Roles of Moonlighting Proteins in Bacteria" Current Issues in Molecular Biology 16, no. 1: 15-22. https://doi.org/10.21775/cimb.016.015

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