Risk Factors for Erosive Esophagitis and Barrett’s Esophagus in a high Helicobacter pylori Prevalence Area
Abstract
Results. EE was diagnosed in 474 patients (11.75%): grade A, in 194 (41%); grade B, in 167 (35%); grade C, in 65 (14%); and grade D, in 48 patients (10%). Increasing severity of erosive esophagitis and presence of its complication – Barrett’s esophagus – were associated with the decreasing prevalence of H. pylori and increasing hiatal hernia size (P<0.05). Male gender (OR, 3.57; 95% CI, 1.12 to 10.62), hiatal hernia >2 cm (OR, 3.73; 95% CI, 1.60 to 8.68), and absence of H. pylori (OR, 4.24; 95% CI, 1.07 to 16.84) were the factors found to be associated with severe EE. The factors associated with BE were as follows: ulcer and/or stricture of esophagus (OR, 11.94; 95% CI, 2.51 to 41.37), age >60 years (OR, 1.06; 95% CI, 1.01 to 1.20), smoking >10 cigarettes per day (OR, 4.62; 95% CI, 1.01 to 12.50), hiatal hernia >2 cm (OR, 5.22; 95% CI, 1.86 to 14.64), and absence of H. pylori (OR, 5.60; 95% CI, 1.38 to 22.72).
Conclusions. The prevalence of EE was found to be low, and the prevalence of BE was found to be very low among routinely endoscoped patients in primary and secondary care settings in a Lithuanian rural area with high H. pylori prevalence. Increasing severity of gastroesophageal reflux disease was associated with the decreasing prevalence of Helicobacter pylori.
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Jonaitis, L.; Kriukas, D.; Kiudelis, G.; Kupčinskas, L. Risk Factors for Erosive Esophagitis and Barrett’s Esophagus in a high Helicobacter pylori Prevalence Area. Medicina 2011, 47, 434. https://doi.org/10.3390/medicina47080065
Jonaitis L, Kriukas D, Kiudelis G, Kupčinskas L. Risk Factors for Erosive Esophagitis and Barrett’s Esophagus in a high Helicobacter pylori Prevalence Area. Medicina. 2011; 47(8):434. https://doi.org/10.3390/medicina47080065
Chicago/Turabian StyleJonaitis, Laimas, Darius Kriukas, Gediminas Kiudelis, and Limas Kupčinskas. 2011. "Risk Factors for Erosive Esophagitis and Barrett’s Esophagus in a high Helicobacter pylori Prevalence Area" Medicina 47, no. 8: 434. https://doi.org/10.3390/medicina47080065