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Case Report

Clinicopathological Features of Churg-Strauss Syndrome With Severe Nerve Degeneration: A Case Report

by
Jing Yan Xiang
1,
Yu Wu Zhao
1,
Jian Liang Fu
1,
Xiao Juan Cheng
1,
Qin Xue
2 and
Yin Wang
3
1
Department of Neurology, Sixth People’s Hospital, Shanghai Jiaotong University
2
Department of Nephrology, Sixth People’s Hospital, Shanghai Jiaotong University
3
Department of Neuropathology, Huashan Hospital, Fudan University, Shanghai, China
Medicina 2012, 48(5), 35; https://doi.org/10.3390/medicina48050035
Submission received: 21 September 2011 / Accepted: 20 May 2012 / Published: 25 May 2012
Versions Notes

Abstract

Churg-Strauss syndrome (CSS) is a rare autoimmune vasculitis of unknown etiology that involves small- and medium-sized blood vessels. Its onset is thought to be associated with adult-onset asthma, and vasculitis typically involves vessels in the lungs. However, due to increased blood and tissue eosinophilia, vasculitis may result in the involvement multiple systems of (neurological, skin, etc.). We report a case of CSS with manifestations that included skin purpura and severe peripheral nerve degeneration in a 56-year-old woman with a recent history of asthma. After the treatment with methylprednisolone and standard immunosuppressive therapy, her rashes resolved, there were no acute asthma attacks, and the numbness in her lower limbs improved.
Keywords: Churg-Strauss syndrome; vasculitis; allergic granulomatosis Churg-Strauss syndrome; vasculitis; allergic granulomatosis

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MDPI and ACS Style

Xiang, J.Y.; Zhao, Y.W.; Fu, J.L.; Cheng, X.J.; Xue, Q.; Wang, Y. Clinicopathological Features of Churg-Strauss Syndrome With Severe Nerve Degeneration: A Case Report. Medicina 2012, 48, 35. https://doi.org/10.3390/medicina48050035

AMA Style

Xiang JY, Zhao YW, Fu JL, Cheng XJ, Xue Q, Wang Y. Clinicopathological Features of Churg-Strauss Syndrome With Severe Nerve Degeneration: A Case Report. Medicina. 2012; 48(5):35. https://doi.org/10.3390/medicina48050035

Chicago/Turabian Style

Xiang, Jing Yan, Yu Wu Zhao, Jian Liang Fu, Xiao Juan Cheng, Qin Xue, and Yin Wang. 2012. "Clinicopathological Features of Churg-Strauss Syndrome With Severe Nerve Degeneration: A Case Report" Medicina 48, no. 5: 35. https://doi.org/10.3390/medicina48050035

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