Association Between Erectile Dysfunction and Asymptomatic Cardiovascular Damage in Middle-Aged Men
Abstract
Material and Methods. In this case-control study, the International Index of Erectile Function (IIEF) questionnaire was employed to assess the erectile function of the study participants and to allocate them either into the ED group (N=21; mean IIEF score, 18.15 [SD, 2.54]; mean age, 48.2 years [SD, 4.4]) or the control group (N=24; mean IIEF score, 23.45 [SD, 0.99]; mean age, 46.8 years [SD, 3.1]). Additionally, pulse wave velocity, augmentation index, pulse pressure, carotid intima media thickness (IMT), and atherosclerotic plaque count were determined, and echocardiography was performed in every subject.
Results. The mean IMT and left ventricular mass index (LVMI) of both carotid arteries in the ED group were significantly higher when compared with controls (598.57 vs. 535.54 mm·10–3, P=0.03, and 107.26 vs. 98.67 g/m2, P=0.04, respectively). Using multiple regression analysis, an independent association between the IIEF score and the LVMI was found (P=0.002). No significant differences in the results of pulse wave velocity, atherosclerotic plaque count, and other laboratory tests were found between the 2 study groups.
Conclusions. The study suggests that ED is associated with a higher LVMI and may be an early marker of CV disease.
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Dženkevičiūtė, V.; Petrulionienė, Ž.; Šapoka, V.; Kasiulevičius, V. Association Between Erectile Dysfunction and Asymptomatic Cardiovascular Damage in Middle-Aged Men. Medicina 2013, 49, 80. https://doi.org/10.3390/medicina49120080
Dženkevičiūtė V, Petrulionienė Ž, Šapoka V, Kasiulevičius V. Association Between Erectile Dysfunction and Asymptomatic Cardiovascular Damage in Middle-Aged Men. Medicina. 2013; 49(12):80. https://doi.org/10.3390/medicina49120080
Chicago/Turabian StyleDženkevičiūtė, Vilma, Žaneta Petrulionienė, Virginijus Šapoka, and Vytautas Kasiulevičius. 2013. "Association Between Erectile Dysfunction and Asymptomatic Cardiovascular Damage in Middle-Aged Men" Medicina 49, no. 12: 80. https://doi.org/10.3390/medicina49120080